Literature DB >> 19731936

Total synthesis of gambierol.

Hiroki Furuta1, Yuki Hasegawa, Yuji Mori.   

Abstract

The total synthesis of gambierol has been achieved utilizing an oxiranyl anion strategy in an iterative manner. Synthetic highlights of this route include direct carbon-carbon formation on epoxides, sulfonyl-assisted 6-endo cyclization, and expansion reaction of tetrahydropyranyl rings to oxepanes to forge the polycyclic architecture of the target molecule.

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Year:  2009        PMID： 19731936     DOI： 10.1021/ol9017408

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

Review 1.  Synthesis of marine polycyclic polyethers via endo-selective epoxide-opening cascades.

Authors:  Ivan Vilotijevic; Timothy F Jamison
Journal:  Mar Drugs       Date:  2010-03-19       Impact factor: 5.118

2.  Synthesis of the EFG Framework of Tamulamides A and B.

Authors:  Elizabeth H Kelley; Timothy F Jamison
Journal:  Org Lett       Date:  2019-09-16       Impact factor: 6.005

Review 3.  Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans.

Authors:  James I Bowen; Luoyi Wang; Matthew P Crump; Christine L Willis
Journal:  Org Biomol Chem       Date:  2022-02-09       Impact factor: 3.876

Review 4.  Ciguatera Mini Review: 21st Century Environmental Challenges and the Interdisciplinary Research Efforts Rising to Meet Them.

Authors:  Christopher R Loeffler; Luciana Tartaglione; Miriam Friedemann; Astrid Spielmeyer; Oliver Kappenstein; Dorina Bodi
Journal:  Int J Environ Res Public Health       Date:  2021-03-15       Impact factor: 3.390
  4 in total

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