A new liquid agent for endovascular embolization: initial clinical experience.

We developed a new water-soluble thermosensitive embolic agent, poly (N-isopropylacrylamide) and performed renal embolization in two cases with renal carcinoma by using this agent. Bleeding stopped immediately after the procedure and did not recur in follow-up intervals except fever because of postinfarction syndrome in these two patients. In one case with bilateral pulmonary metastasis, there was partial recanalization in superior segmental artery 1 month later, and this patient died 5 months after embolization due to deterioration in his general condition. The other patient refused further treatment and remained alive during 5-month follow-up interval. We believe that this agent has a great potentiality and will become a new liquid embolic material in endovascular treatment of renal carcinoma and vascular diseases.