Literature DB >> 19729906

Mortality trends associated with acute renal failure requiring dialysis after CABG surgery in the United States.

Alina Nicoara1, Uptal D Patel, Barbara G Phillips-Bute, Andrew D Shaw, Mark Stafford-Smith, Carmelo A Milano, Madhav Swaminathan.   

Abstract

BACKGROUND/AIMS: Acute renal failure is associated with a high risk of mortality when it complicates coronary artery bypass graft (CABG) surgery. We examined a large nationwide database from 1988 to 2003 and hypothesized that mortality in CABG-associated acute renal failure needing dialysis (ARF-D) had declined during this period.
METHODS: The Nationwide Inpatient Sample containing data on inpatient stays across 20% of US hospitals was used for our study. Multivariate logistic regression was used to determine an association between year and ARF-D mortality with standardized risk adjustment.
RESULTS: Incidence of ARF-D increased from 0.2 to 0.6% while mortality simultaneously decreased from 47.4% in 1988 to 29.7% in 2003. In the multivariable model, year was significantly associated with declining ARF-D mortality.
CONCLUSIONS: The incidence of post-CABG ARF-D more than doubled from 1988 to 2003, while mortality simultaneously decreased by over one-third. Improved survival after ARF-D following CABG may be counterbalanced by increased morbidity and resource utilization. Copyright 2009 S. Karger AG, Basel.

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Year:  2009        PMID: 19729906     DOI: 10.1159/000235856

Source DB:  PubMed          Journal:  Blood Purif        ISSN: 0253-5068            Impact factor:   2.614


  6 in total

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  6 in total

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