BACKGROUND/AIM: Volume expansion in peritoneal dialysis (PD) patients is associated with left ventricular hypertrophy. The link between inflammation and hypervolemia has not been extensively studied. The aim of this study was to determine if an association exists between hypervolemia and markers of inflammation in PD patients. METHODS: In this cross-sectional study of 22 prevalent PD patients, volume was determined by bioelectrical impedance analysis. Serum and peritoneal effluent interleukin-6 (IL-6) and peritoneal transforming growth factor (TGF)-beta(1) were measured. A fast peritoneal equilibration test determined peritoneal transport status. RESULTS: Bioimpedance-derived measures of hypervolemia correlated with peritoneal effluent IL-6 and TGF-beta(1). Peritoneal IL-6 was also associated with high peritoneal transport status. CONCLUSIONS: Markers of inflammation and fibrosis (peritoneal IL-6 and TGF-beta(1)) are associated with markers of hypervolemia. Copyright 2009 S. Karger AG, Basel.
BACKGROUND/AIM: Volume expansion in peritoneal dialysis (PD) patients is associated with left ventricular hypertrophy. The link between inflammation and hypervolemia has not been extensively studied. The aim of this study was to determine if an association exists between hypervolemia and markers of inflammation in PDpatients. METHODS: In this cross-sectional study of 22 prevalent PDpatients, volume was determined by bioelectrical impedance analysis. Serum and peritoneal effluent interleukin-6 (IL-6) and peritoneal transforming growth factor (TGF)-beta(1) were measured. A fast peritoneal equilibration test determined peritoneal transport status. RESULTS: Bioimpedance-derived measures of hypervolemia correlated with peritoneal effluent IL-6 and TGF-beta(1). Peritoneal IL-6 was also associated with high peritoneal transport status. CONCLUSIONS: Markers of inflammation and fibrosis (peritoneal IL-6 and TGF-beta(1)) are associated with markers of hypervolemia. Copyright 2009 S. Karger AG, Basel.
Authors: C Demirci; G Aşcı; M S Demirci; M Özkahya; H Töz; S Duman; S Sipahi; S Erten; M Tanrısev; E Ok Journal: Int Urol Nephrol Date: 2016-04-19 Impact factor: 2.370
Authors: Jesús Loureiro; Abelardo Aguilera; Rafael Selgas; Pilar Sandoval; Patricia Albar-Vizcaíno; María Luisa Pérez-Lozano; Vicente Ruiz-Carpio; Pedro L Majano; Santiago Lamas; Fernando Rodríguez-Pascual; Francisco Borras-Cuesta; Javier Dotor; Manuel López-Cabrera Journal: J Am Soc Nephrol Date: 2011-07-08 Impact factor: 10.121
Authors: Wim Van Biesen; John D Williams; Adrian C Covic; Stanley Fan; Kathleen Claes; Monika Lichodziejewska-Niemierko; Christian Verger; Jurg Steiger; Volker Schoder; Peter Wabel; Adelheid Gauly; Rainer Himmele Journal: PLoS One Date: 2011-02-24 Impact factor: 3.240
Authors: Jesús Loureiro; Guadalupe Gónzalez-Mateo; José Jimenez-Heffernan; Rafael Selgas; Manuel López-Cabrera; Abelardo Aguilera Peralta Journal: Int J Nephrol Date: 2013-02-10