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Literature DB >> 19728022

Two rare MPL gene mutations in patients with essential thrombocythemia.

Haruhiko Ohashi¹, Kayoko Arita², Shoko Fukami², Kayo Oguri², Hirokazu Nagai², Toshiya Yokozawa², Tomomitsu Hotta², Shuichi Hanada³.

Abstract

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19728022 DOI： 10.1007/s12185-009-0413-3

Source DB: PubMed Journal: Int J Hematol ISSN： 0925-5710 Impact factor: 2.490

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7 in total

Review 1. Genetic complexity of myeloproliferative neoplasms.

Authors: R Kralovics
Journal: Leukemia Date: 2008-08-28 Impact factor: 11.528

2. An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

Authors: Judith Staerk; Catherine Lacout; Takeshi Sato; Steven O Smith; William Vainchenker; Stefan N Constantinescu
Journal: Blood Date: 2005-10-25 Impact factor: 22.113

3. MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients.

Authors: Animesh D Pardanani; Ross L Levine; Terra Lasho; Yana Pikman; Ruben A Mesa; Martha Wadleigh; David P Steensma; Michelle A Elliott; Alexandra P Wolanskyj; William J Hogan; Rebecca F McClure; Mark R Litzow; D Gary Gilliland; Ayalew Tefferi
Journal: Blood Date: 2006-07-25 Impact factor: 22.113

4. Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin.

Authors: Jianmin Ding; Hirokazu Komatsu; Atsushi Wakita; Miyuki Kato-Uranishi; Masato Ito; Atsushi Satoh; Kazuya Tsuboi; Masakazu Nitta; Hiroshi Miyazaki; Shinsuke Iida; Ryuzo Ueda
Journal: Blood Date: 2004-02-05 Impact factor: 22.113

5. New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition.

Authors: R Chaligné; C Tonetti; R Besancenot; L Roy; C Marty; P Mossuz; J-J Kiladjian; G Socié; D Bordessoule; M-C Le Bousse-Kerdilès; W Vainchenker; S Giraudier
Journal: Leukemia Date: 2008-06-05 Impact factor: 11.528

6. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.

Authors: Yana Pikman; Benjamin H Lee; Thomas Mercher; Elizabeth McDowell; Benjamin L Ebert; Maricel Gozo; Adam Cuker; Gerlinde Wernig; Sandra Moore; Ilene Galinsky; Daniel J DeAngelo; Jennifer J Clark; Stephanie J Lee; Todd R Golub; Martha Wadleigh; D Gary Gilliland; Ross L Levine
Journal: PLoS Med Date: 2006-07 Impact factor: 11.069

7. MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.

Authors: Philip A Beer; Peter J Campbell; Linda M Scott; Anthony J Bench; Wendy N Erber; David Bareford; Bridget S Wilkins; John T Reilly; Hans C Hasselbalch; Richard Bowman; Keith Wheatley; Georgina Buck; Claire N Harrison; Anthony R Green
Journal: Blood Date: 2008-05-01 Impact factor: 22.113

7 in total

4 in total

Two rare MPL gene mutations in patients with essential thrombocythemia.

Review 1. Genetic complexity of myeloproliferative neoplasms.

2. An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

3. MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients.

4. Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin.

5. New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition.

6. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.

7. MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.

1. Spontaneous regression of essential thrombocythemia with MPL mutation on menopause.

2. Two activating mutations of MPL in triple-negative myeloproliferative neoplasms.

Review 3. Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases.

4. Nonfamilial, MPL S505N-Mutated Essential Thrombocythaemia.