Literature DB >> 1972777

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.

M H Rosner1, M A Vigano, K Ozato, P M Timmons, F Poirier, P W Rigby, L M Staudt.   

Abstract

The murine oct-3 gene encodes a transcription factor containing a POU-specific domain and a homeodomain. In marked contrast to other homeodomain-encoding genes, oct-3 is expressed in the totipotent and pluripotent stem cells of the pregastrulation embryo and is down-regulated during differentiation to endoderm and mesoderm, suggesting that it has a role in early development. The oct-3 gene is also expressed in primordial germ cells and in the female germ line.

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Year:  1990        PMID： 1972777     DOI： 10.1038/345686a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  247 in total

1.  Specific down-regulation of annexin II expression in human cells interferes with cell proliferation.

Authors:  Y Chiang; A Rizzino; Z A Sibenaller; M S Wold; J K Vishwanatha
Journal:  Mol Cell Biochem       Date:  1999-09       Impact factor: 3.396

2.  Repression of Ets-2-induced transactivation of the tau interferon promoter by Oct-4.

Authors:  T Ezashi; D Ghosh; R M Roberts
Journal:  Mol Cell Biol       Date:  2001-12       Impact factor: 4.272

3.  Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

Authors:  Hitoshi Niwa; Shinji Masui; Ian Chambers; Austin G Smith; Jun-ichi Miyazaki
Journal:  Mol Cell Biol       Date:  2002-03       Impact factor: 4.272

4.  Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo.

Authors:  Lynn A Hanna; Ruth K Foreman; Illya A Tarasenko; Daniel S Kessler; Patricia A Labosky
Journal:  Genes Dev       Date:  2002-10-15       Impact factor: 11.361

5.  Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity.

Authors:  Tetsuya S Tanaka; Tilo Kunath; Wendy L Kimber; Saied A Jaradat; Carole A Stagg; Masayuki Usuda; Takashi Yokota; Hitoshi Niwa; Janet Rossant; Minoru S H Ko
Journal:  Genome Res       Date:  2002-12       Impact factor: 9.043

6.  Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation.

Authors:  Mary C Trask; Kimberly D Tremblay; Jesse Mager
Journal:  Dev Biol       Date:  2012-06-02       Impact factor: 3.582

7.  Use of mouse hematopoietic stem and progenitor cells to treat acute kidney injury.

Authors:  Ling Li; Rachel Black; Zhendong Ma; Qiwen Yang; Andrew Wang; Fangming Lin
Journal:  Am J Physiol Renal Physiol       Date:  2011-09-21

8.  Genesis of embryonic stem cells.

Authors:  Mia Buehr; Austin Smith
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2003-08-29       Impact factor: 6.237

9.  Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex.

Authors:  Mizuho Tomioka; Masazumi Nishimoto; Satoru Miyagi; Tomoko Katayanagi; Nobutaka Fukui; Hitoshi Niwa; Masami Muramatsu; Akihiko Okuda
Journal:  Nucleic Acids Res       Date:  2002-07-15       Impact factor: 16.971

10.  Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer.

Authors:  L Dailey; H Yuan; C Basilico
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272
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