Literature DB >> 1972693

Regional localization by in situ hybridization of a human chromosome 9 marker tightly linked to the Friedreich's ataxia locus.

E Raimondi1, A Antonelli, A J Driesel, M Pandolfo.   

Abstract

In order to determine the regional localization of the Friedreich's ataxia (FA) gene on chromosome 9, the DNA probe DR47 (D9S5), which detects a restriction fragment length polymorphism (RFLP) in tight linkage with the disease, was hybridized in situ to metaphase chromosomes. Our results enable the D9S5 locus to be assigned to the 9q12-q13 region, thus indicating that this is also the localization of the FA gene.

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Year:  1990        PMID： 1972693     DOI： 10.1007/bf00276338

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  5 in total

1.  Clinical description and roentgenologic evaluation of patients with Friedreich's ataxia.

Authors:  G Geoffroy; A Barbeau; G Breton; B Lemieux; M Aube; C Leger; J P Bouchard
Journal:  Can J Neurol Sci       Date:  1976-11       Impact factor: 2.104

2.  Confirmation of linkage of Friedreich ataxia to chromosome 9 and identification of a new closely linked marker.

Authors:  R Fujita; Y Agid; P Trouillas; A Seck; C Tommasi-Davenas; A J Driesel; K Olek; K H Grzeschik; Y Nakamura; J L Mandel; A Hanauer
Journal:  Genomics       Date:  1989-01       Impact factor: 5.736

3.  Mapping of mutation causing Friedreich's ataxia to human chromosome 9.

Authors:  S Chamberlain; J Shaw; A Rowland; J Wallis; S South; Y Nakamura; A von Gabain; M Farrall; R Williamson
Journal:  Nature       Date:  1988-07-21       Impact factor: 49.962

4.  Regional mapping of the human placental alkaline phosphatase gene (ALPP) to 2q37 by in situ hybridization.

Authors:  E Raimondi; D Talarico; L Moro; W J Rutter; G Della Valle; L De Carli
Journal:  Cytogenet Cell Genet       Date:  1988

5.  Genetic homogeneity at the Friedreich ataxia locus on chromosome 9.

Authors:  S Chamberlain; J Shaw; J Wallis; A Rowland; L Chow; M Farrall; B Keats; A Richter; M Roy; S Melancon
Journal:  Am J Hum Genet       Date:  1989-04       Impact factor: 11.025
  5 in total
  1 in total

1.  Localization of DNA probes tightly linked to the Friedreich's ataxia locus by in situ hybridization in a case of pericentric inversion of chromosome 9.

Authors:  E Raimondi; P Bernasconi; D Moralli; R Fujita; G Uziel; S Di Donato; L De Carli; M Pandolfo
Journal:  Hum Genet       Date:  1991-03       Impact factor: 4.132
  1 in total

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