Literature DB >> 19726434

Retinal drusen: harbingers of age, safe havens for trouble.

M A Williams1, D Craig, P Passmore, G Silvestri.   

Abstract

Drusen are small focal extracellular deposits underneath the retina, visible ophthalmoscopically as yellow dots. The more hard drusen there are, the greater the risk of developing soft drusen and retinal pigmentary changes, which in turn increase the risk of developing advanced age-related macular degeneration. Much remains to be discovered about drusen. For the patient with drusen, basic advice on diet and smoking and maintenance of a high level of vigilance for visual changes is appropriate management.

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Year:  2009        PMID： 19726434     DOI： 10.1093/ageing/afp136

Source DB:  PubMed          Journal:  Age Ageing        ISSN： 0002-0729            Impact factor:   10.668


  11 in total

Review 1.  Molecular imaging of retinal disease.

Authors:  Megan E Capozzi; Andrew Y Gordon; John S Penn; Ashwath Jayagopal
Journal:  J Ocul Pharmacol Ther       Date:  2013-02-19       Impact factor: 2.671

2.  Characteristics of morphologic macular abnormalities in neuroimmunology practice.

Authors:  Omar Al-Louzi; Elias S Sotirchos; Angela Vidal-Jordana; Shin C Beh; Julia Button; Howard S Ying; Laura J Balcer; Elliot M Frohman; Shiv Saidha; Peter A Calabresi; Scott D Newsome
Journal:  Mult Scler       Date:  2017-11-10       Impact factor: 6.312

3.  The incidental findings of age-related macular degeneration during diabetic retinopathy screening.

Authors:  Rita Gangwani; Wico W Lai; Rita Sum; Sarah M McGhee; Catherine W S Chan; Anthony J Hedley; David Wong
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-11-27       Impact factor: 3.117

4.  Spectral-domain optical coherence tomography characteristics of intermediate age-related macular degeneration.

Authors:  Jessica N Leuschen; Stefanie G Schuman; Katrina P Winter; Michelle N McCall; Wai T Wong; Emily Y Chew; Thomas Hwang; Sunil Srivastava; Neeru Sarin; Traci Clemons; Molly Harrington; Cynthia A Toth
Journal:  Ophthalmology       Date:  2012-09-08       Impact factor: 12.079

5.  Bowman lecture on the role of inflammation in degenerative disease of the eye.

Authors:  J V Forrester
Journal:  Eye (Lond)       Date:  2013-01-04       Impact factor: 3.775

6.  Enhanced Detection of Sub-Retinal Pigment Epithelial Cell Layer Deposits in Human and Murine Tissue: Imaging Zinc as a Biomarker for Age-Related Macular Degeneration (An American Ophthalmological Society Thesis).

Authors:  Frederik J G M van Kuijk; Scott W McPherson; Heidi Roehrich
Journal:  Trans Am Ophthalmol Soc       Date:  2017-08-22

7.  Comment on "Drusen and pachydrusen: the definition, pathogenesis, and clinical significance".

Authors:  Jay Sheth
Journal:  Eye (Lond)       Date:  2021-05-27       Impact factor: 3.775

Review 8.  Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases.

Authors:  Mika Reinisalo; Anna Kårlund; Ali Koskela; Kai Kaarniranta; Reijo O Karjalainen
Journal:  Oxid Med Cell Longev       Date:  2015-06-09       Impact factor: 6.543

9.  Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity.

Authors:  Nicole T M Saksens; Mark P Krebs; Frederieke E Schoenmaker-Koller; Wanda Hicks; Minzhong Yu; Lanying Shi; Lucy Rowe; Gayle B Collin; Jeremy R Charette; Stef J Letteboer; Kornelia Neveling; Tamara W van Moorsel; Sleiman Abu-Ltaif; Elfride De Baere; Sophie Walraedt; Sandro Banfi; Francesca Simonelli; Frans P M Cremers; Camiel J F Boon; Ronald Roepman; Bart P Leroy; Neal S Peachey; Carel B Hoyng; Patsy M Nishina; Anneke I den Hollander
Journal:  Nat Genet       Date:  2015-12-21       Impact factor: 38.330

Review 10.  Present and possible therapies for age-related macular degeneration.

Authors:  Muhammad Khan; Ketan Agarwal; Mohamed Loutfi; Ahmed Kamal
Journal:  ISRN Ophthalmol       Date:  2014-04-16
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