Literature DB >> 19726183

Solvent free synthesis of 1,5-disubstituted tetrazoles derived from Baylis Hillman acetates as potential TNF-alpha inhibitors.

P Srihari1, Palash Dutta, R Srinivasa Rao, J S Yadav, S Chandrasekhar, P Thombare, J Mohapatra, A Chatterjee, Mukul R Jain.   

Abstract

Solvent free multicomponent reaction of Baylis Hillman acetate, TMS azide and arylnitrile to produce 1,5-disubstituted tetrazole is described. Some of these tetrazoles are found to be potential TNF-alpha inhibitors.

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Year:  2009        PMID： 19726183     DOI： 10.1016/j.bmcl.2009.08.047

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

Review 1.  A review of syntheses of 1,5-disubstituted tetrazole derivatives.

Authors:  Afshin Sarvary; Ali Maleki
Journal:  Mol Divers       Date:  2014-10-02       Impact factor: 2.943

2.  Humic acid as an efficient and reusable catalyst for one pot three-component green synthesis of 5-substituted 1H-tetrazoles in water.

Authors:  Hongshe Wang; Yichun Wang; Yinfeng Han; Weixing Zhao; Xiaomei Wang
Journal:  RSC Adv       Date:  2020-01-03       Impact factor: 4.036
  2 in total

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