OBJECTIVE: We investigated the change of antipsychotic treatment of elderly persons with dementia after several publications indicated an association between use of antipsychotics and cerebrovascular events in this population. METHODS: Twice a year, the complete medication, age, diagnosis and gender of all inpatients in 30 German psychiatric sites is collected anonymously in a data base for statistical analysis. RESULTS: The treatment changed for the benefit of Quetiapine and Haloperidol. The use of both Risperidone and Olanzapine decreased markedly. CONCLUSION: The antipsychotic treatment changed due to critical publication. But, the evidence for the risk profile is still a matter of debate.
OBJECTIVE: We investigated the change of antipsychotic treatment of elderly persons with dementia after several publications indicated an association between use of antipsychotics and cerebrovascular events in this population. METHODS: Twice a year, the complete medication, age, diagnosis and gender of all inpatients in 30 German psychiatric sites is collected anonymously in a data base for statistical analysis. RESULTS: The treatment changed for the benefit of Quetiapine and Haloperidol. The use of both Risperidone and Olanzapine decreased markedly. CONCLUSION: The antipsychotic treatment changed due to critical publication. But, the evidence for the risk profile is still a matter of debate.
Authors: H-J Gertz; G Stoppe; B Müller-Oerlinghausen; L G Schmidt; C Baethge; C Hiemke; K Lieb; T Bschor Journal: Nervenarzt Date: 2013-03 Impact factor: 1.214