Literature DB >> 19724722

Severely Mood-disordered Youth Respond Less Well to Treatment in a Community Clinic than Youth with Bipolar Disorder.

Leo Bastiaens1, Jesse Bastiaens.   

Abstract

OBJECTIVE: A tremendous increase in the diagnosis of bipolar disorder in pediatrics raises questions about current diagnostic practices. Even though researchers are providing initial follow-up data about rigorously diagnosed bipolar youth versus youth with severe nonbipolar mood symptomatology, not much is known about these different patient groups in the community. This study used standardized assessment tools to evaluate if meaningful differences emerge between different mood disorder types in children.
DESIGN: The Mini International Neuropsychiatric Interview and the Child/Adolescent Symptom Inventory were used to classify patients as having bipolar disorder or mood disorder not otherwise specified (NOS) according to criteria set forth by the National Institute of Mental Health. A retrospective chart review followed back the treatment for eight months.
SETTING: A community mental health clinic. PARTICIPANTS: 41 pediatric patients between six and 18 years old. MEASUREMENTS: Global Assessment of Functioning scale and Clinical Global Impression scales were compared pre- and post-treatment.
RESULTS: Patients with bipolar disorder improved significantly more than mood disorder NOS patients, despite similar levels of care. Meaningful differences in diagnostic and treatment variables were apparent at baseline and at endpoint.
CONCLUSION: Standardized assessments in community clinics are feasible and lead to the identification of meaningful differences between "similar" patient groups. Improving diagnostic practices across different psychiatric settings appears paramount.

Entities:  

Keywords:  bipolar disorder; diagnosis; mood disorder NOS; pediatric; treatment response

Year:  2008        PMID: 19724722      PMCID: PMC2731676     

Source DB:  PubMed          Journal:  Psychiatry (Edgmont)        ISSN: 1550-5952


  10 in total

1.  Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulation.

Authors:  Melissa A Brotman; Layla Kassem; Michelle M Reising; Amanda E Guyer; Daniel P Dickstein; Brendan A Rich; Kenneth E Towbin; Daniel S Pine; Francis J McMahon; Ellen Leibenluft
Journal:  Am J Psychiatry       Date:  2007-08       Impact factor: 18.112

2.  Scientists probe child bipolar disorder.

Authors:  Bridget M Kuehn
Journal:  JAMA       Date:  2007-03-21       Impact factor: 56.272

3.  Who are the children with severe mood dysregulation, a.k.a. "rages"?

Authors:  Gabrielle A Carlson
Journal:  Am J Psychiatry       Date:  2007-08       Impact factor: 18.112

4.  Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children.

Authors:  Melissa A Brotman; Mariana Schmajuk; Brendan A Rich; Daniel P Dickstein; Amanda E Guyer; E Jane Costello; Helen L Egger; Adrian Angold; Daniel S Pine; Ellen Leibenluft
Journal:  Biol Psychiatry       Date:  2006-11-01       Impact factor: 13.382

5.  Phenomenology of prepubertal and early adolescent bipolar disorder: examples of elated mood, grandiose behaviors, decreased need for sleep, racing thoughts and hypersexuality.

Authors:  Barbara Geller; Betsy Zimerman; Marlene Williams; Melissa P Delbello; Jeanne Frazier; Linda Beringer
Journal:  J Child Adolesc Psychopharmacol       Date:  2002       Impact factor: 2.576

6.  Different psychophysiological and behavioral responses elicited by frustration in pediatric bipolar disorder and severe mood dysregulation.

Authors:  Brendan A Rich; Mariana Schmajuk; Koraly E Perez-Edgar; Nathan A Fox; Daniel S Pine; Ellen Leibenluft
Journal:  Am J Psychiatry       Date:  2007-02       Impact factor: 18.112

7.  Increased rates of bipolar disorder diagnoses among U.S. child, adolescent, and adult inpatients, 1996-2004.

Authors:  Joseph C Blader; Gabrielle A Carlson
Journal:  Biol Psychiatry       Date:  2007-02-16       Impact factor: 13.382

Review 8.  Defining clinical phenotypes of juvenile mania.

Authors:  Ellen Leibenluft; Dennis S Charney; Kenneth E Towbin; Robinder K Bhangoo; Daniel S Pine
Journal:  Am J Psychiatry       Date:  2003-03       Impact factor: 18.112

9.  A non-randomized, open study with aripiprazole and ziprasidone for the treatment of aggressive behavior in youth in a community clinic.

Authors:  Leo Bastiaens
Journal:  Community Ment Health J       Date:  2008-07-03

Review 10.  Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosis.

Authors:  Eric A Youngstrom; Boris Birmaher; Robert L Findling
Journal:  Bipolar Disord       Date:  2008-02       Impact factor: 6.744

  10 in total
  2 in total

1.  The affective storms of school children during night time: do affective dysregulated school children show a specific pattern of sleep disturbances?

Authors:  Tanja Legenbauer; Sarah Heiler; Martin Holtmann; Leonie Fricke-Oerkermann; Gerd Lehmkuhl
Journal:  J Neural Transm (Vienna)       Date:  2012-06-09       Impact factor: 3.575

Review 2.  A systematic review of mental health outcome measures for young people aged 12 to 25 years.

Authors:  Benjamin Kwan; Debra J Rickwood
Journal:  BMC Psychiatry       Date:  2015-11-14       Impact factor: 3.630

  2 in total

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