Literature DB >> 1972358

Pharmacology and clinical pharmacology of organic nitrates.

H Grobecker1.   

Abstract

Current concepts and future aspects of pharmacological interventions in the treatment of coronary heart disease have been compiled. Especially new insights in the pathophysiology of coronary heart disease e.g. the dynamic pathology of coronary atherosclerosis, possible role of endothelin in vasospasm, as well as new pharmacodynamic and pharmacokinetic aspects of organic nitrates are discussed. Also the role of sympathetic nervous system as a pivotal question in pathophysiology and clinical pharmacology in the treatment of angina pectoris has been considered.

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Year:  1990        PMID： 1972358     DOI： 10.1007/bf01417558

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  15 in total

1.  Arteriographic demonstration of coronary artery spasm and its release after the use of a vasodilator in a case of angina pectoris and in the experimental animal.

Authors:  G G GENSINI; S DI GIORGI; S MURAD-NETTO; A BLACK
Journal:  Angiology       Date:  1962-12       Impact factor: 3.619

2.  A novel potent vasoconstrictor peptide produced by vascular endothelial cells.

Authors:  M Yanagisawa; H Kurihara; S Kimura; Y Tomobe; M Kobayashi; Y Mitsui; Y Yazaki; K Goto; T Masaki
Journal:  Nature       Date:  1988-03-31       Impact factor: 49.962

3.  Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

Authors:  L J Ignarro; H Lippton; J C Edwards; W H Baricos; A L Hyman; P J Kadowitz; C A Gruetter
Journal:  J Pharmacol Exp Ther       Date:  1981-09       Impact factor: 4.030

4.  Coronary vasospasm. Observations linking the clinical spectrum of ischemic heart disease to the dynamic pathology of coronary atherosclerosis.

Authors:  B G Brown
Journal:  Arch Intern Med       Date:  1981-05

5.  Tolerance to the vascular effects of glyceryl trinitrate.

Authors:  P Needleman
Journal:  J Pharmacol Exp Ther       Date:  1970-01       Impact factor: 4.030

Review 6.  Unloading the heart in congestive heart failure.

Authors:  J N Cohn
Journal:  Am J Med       Date:  1984-08-20       Impact factor: 4.965

7.  Transdermal nitroglycerin in angina pectoris.

Authors:  J O Parker; H L Fung
Journal:  Am J Cardiol       Date:  1984-09-01       Impact factor: 2.778

8.  Comparative effects of glyceryl trinitrate on venous and arterial smooth muscle in vitro; relevance to antianginal activity.

Authors:  J E Mackenzie; J R Parratt
Journal:  Br J Pharmacol       Date:  1977-05       Impact factor: 8.739

9.  Angina pectoris. I. A variant form of angina pectoris; preliminary report.

Authors:  M PRINZMETAL; R KENNAMER; R MERLISS; T WADA; N BOR
Journal:  Am J Med       Date:  1959-09       Impact factor: 4.965

10.  Evaluation of the effects of systemic nitroglycerin on perfusion of ischemic myocardium in coronary heart disease assessed intraoperatively by antegrade blood flow through intact saphenous vein bypass grafts.

Authors:  R C Klein; T M Grehl; K B Stengert; D T Mason
Journal:  Am Heart J       Date:  1981-03       Impact factor: 4.749
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  1 in total

Review 1.  Autonomic dysreflexia after spinal cord injury: Systemic pathophysiology and methods of management.

Authors:  Khalid C Eldahan; Alexander G Rabchevsky
Journal:  Auton Neurosci       Date:  2017-05-08       Impact factor: 3.145
  1 in total

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