| Literature DB >> 19723490 |
Abstract
Lipoprotein cholesterol is mobilized from lysosomes by actions of the NPC1 and NPC2 proteins. In this issue of Cell Metabolism, Harrison et al. report on identification of an NPC2-interacting protein, the Nogo-B receptor, that regulates NPC2 protein levels. NPC2 stabilization may represent a novel mechanism through which cells respond to endocytosed cholesterol.Entities:
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Year: 2009 PMID： 19723490 DOI： 10.1016/j.cmet.2009.08.006
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287