Literature DB >> 19722896

DNA vaccines against mycobacterial diseases.

Marta Romano1, Kris Huygen.   

Abstract

Bacteria belonging to the genus Mycobacterium can cause several infectious diseases affecting humans and animals. Here, we reviewed the latest advances in the development of DNA vaccines against TB, Buruli ulcer and Johne's disease. Current understanding of the immunity to the respective causative pathogens indicates that the use of DNA vaccines encoding mycobacterial antigens could lead to efficient vaccination strategies. Moreover, characterization of protective mycobacterial antigens has been greatly facilitated by the analysis of immune responses induced after DNA vaccination. In addition, work aiming at optimizing DNA vaccines against mycobacterial diseases and research related to the controversial development of postexposure and therapeutic DNA vaccines are also discussed.

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Year:  2009        PMID： 19722896     DOI： 10.1586/erv.09.87

Source DB:  PubMed          Journal:  Expert Rev Vaccines        ISSN： 1476-0584            Impact factor:   5.217


  10 in total

1.  Vaccine strategies against cystic fibrosis pathogens.

Authors:  Vincent Le Moigne; Jean-Louis Gaillard; Jean-Louis Herrmann
Journal:  Hum Vaccin Immunother       Date:  2016-03-03       Impact factor: 3.452

2.  Inhalation of recombinant adenovirus expressing granulysin protects mice infected with Mycobacterium tuberculosis.

Authors:  J Ma; J Lu; H Huang; X Teng; M Tian; Q Yu; X Yuan; Y Jing; C Shi; J Li; X Fan
Journal:  Gene Ther       Date:  2015-07-16       Impact factor: 5.250

Review 3.  DNA vaccines for targeting bacterial infections.

Authors:  Mariana Ingolotti; Omkar Kawalekar; Devon J Shedlock; Karuppiah Muthumani; David B Weiner
Journal:  Expert Rev Vaccines       Date:  2010-07       Impact factor: 5.217

4.  High mobility group box 1 acts as an adjuvant for tuberculosis subunit vaccines.

Authors:  Ajay Grover; Jolynn Troudt; Chad Foster; Randall Basaraba; Angelo Izzo
Journal:  Immunology       Date:  2014-05       Impact factor: 7.397

5.  A single dose of a DNA vaccine encoding apa coencapsulated with 6,6'-trehalose dimycolate in microspheres confers long-term protection against tuberculosis in Mycobacterium bovis BCG-primed mice.

Authors:  Dyego Carlétti; Denise Morais da Fonseca; Ana Flávia Gembre; Ana Paula Masson; Lívia Weijenborg Campos; Luciana C C Leite; Andréa Rodrigues Pires; Joseli Lannes-Vieira; Célio Lopes Silva; Vânia Luiza Deperon Bonato; Cynthia Horn
Journal:  Clin Vaccine Immunol       Date:  2013-06-05

6.  Boosting BCG-primed mice with chimeric DNA vaccine HG856A induces potent multifunctional T cell responses and enhanced protection against Mycobacterium tuberculosis.

Authors:  Ping Ji; Zhi-Dong Hu; Han Kang; Qin Yuan; Hui Ma; Han-Li Wen; Juan Wu; Zhong-Ming Li; Douglas B Lowrie; Xiao-Yong Fan
Journal:  Immunol Res       Date:  2016-02       Impact factor: 4.505

7.  Immunogenicity and protective efficacy against murine tuberculosis of a prime-boost regimen with BCG and a DNA vaccine expressing ESAT-6 and Ag85A fusion protein.

Authors:  Jia Lu; Chun Wang; Zhiguang Zhou; Ying Zhang; Tingting Cao; Chunwei Shi; Zhenhua Chen; Lingxia Chen; Changxue Cai; Xionglin Fan
Journal:  Clin Dev Immunol       Date:  2011-02-27

8.  Evaluation of the eukaryotic expression of mtb32C-hbha fusion gene of Mycobacterium tuberculosis in Hepatocarcinoma cell line.

Authors:  Roghayeh Teimourpour; Hosna Zare; Ramazan Rajabnia; Yousef Yahyapour; Zahra Meshkat
Journal:  Iran J Microbiol       Date:  2016-04

9.  Adjunctive immunotherapy with α-crystallin based DNA vaccination reduces Tuberculosis chemotherapy period in chronically infected mice.

Authors:  Priyanka Chauhan; Ruchi Jain; Bappaditya Dey; Anil K Tyagi
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379

10.  Enhanced tuberculosis clearance through the combination treatment with recombinant adenovirus-mediated granulysin delivery.

Authors:  Ling Hao; Jilei Ma; Chunwei Shi; Xiaosong Lin; Yandi Zhang; Banga Ndzouboukou Jo-Lewis; Qing Lei; Nadeem Ullah; Zhongjie Yao; Xionglin Fan
Journal:  Theranostics       Date:  2020-08-08       Impact factor: 11.556
  10 in total

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