Literature DB >> 19721862

Paraquat intoxication in subjects who attempt suicide: why they chose paraquat.

Su-Jin Seok1, Hyo-Wook Gil, Du-Shin Jeong, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong.   

Abstract

BACKGROUND/AIMS: Paraquat (PQ) has been used in suicide attempts; an estimated 2,000 toxic ingestions occur annually, with 60-70% mortality. We sought to determine why PQ is such a common agent for suicide attempts in Korea.
METHODS: We analyzed 250 cases (143 males, 107 females) of attempted suicide by PQ ingestion from January to December 2007. The procurement of the PQ was divided into two categories: purchased and preexisting.
RESULTS: Men were more likely to have purchased PQ than women (66% vs. 22%, p=0.042). Additionally, men were more likely to be unmarried (n=34, 23.9% vs. n=10, 9.3%) or divorced or separated (n=16, 11.3% vs. n=5, 4.6%) than the women (p<0.001). The group who intentionally selected PQ (38.4%) consisted of 96 cases (54 males, 42 females) and the group who did not intentionally select PQ (61.6%) included 154 cases (89 males, 65 females). The incidence of PQ purchase was higher in the intentional selection PQ group (46.9% vs. 18.2%, p<0.01).
CONCLUSIONS: Only 38% of patients who attempted suicide with PQ intentionally selected PQ. Thus, greater control of PQ availability is needed, especially in patients at risk.

Entities:  

Keywords:  Paraquat; Suicide, attempted

Mesh:

Substances:

Year:  2009        PMID: 19721862      PMCID: PMC2732785          DOI: 10.3904/kjim.2009.24.3.247

Source DB:  PubMed          Journal:  Korean J Intern Med        ISSN: 1226-3303            Impact factor:   2.884


  12 in total

1.  A prospective clinical trial of pulse therapy with glucocorticoid and cyclophosphamide in moderate to severe paraquat-poisoned patients.

Authors:  J L Lin; M L Leu; Y C Liu; G H Chen
Journal:  Am J Respir Crit Care Med       Date:  1999-02       Impact factor: 21.405

2.  Inhibition of paraquat accumulation in rat lung slices by a component of rat plasma and a variety of drugs and endogenous amines.

Authors:  E A Lock; L L Smith; M S Rose
Journal:  Biochem Pharmacol       Date:  1976-08-01       Impact factor: 5.858

3.  Effect of vitamin C on plasma total antioxidant status in patients with paraquat intoxication.

Authors:  Sae Yong Hong; Kyu Yoon Hwang; Eun Young Lee; Soo Whon Eun; Suk Ran Cho; Chan Soo Han; Yung Hyun Park; Sung Keun Chang
Journal:  Toxicol Lett       Date:  2002-01-05       Impact factor: 4.372

4.  Resolution after radiotherapy of severe pulmonary damage due to paraquat poisoning.

Authors:  D B Webb; M V Williams; B H Davies; K W James
Journal:  Br Med J (Clin Res Ed)       Date:  1984-04-28

5.  Structure-activity correlations of amines inhibiting active uptake of paraquat (methyl viologen) into rat lung slices.

Authors:  J H Ross; R I Krieger
Journal:  Toxicol Appl Pharmacol       Date:  1981-06-30       Impact factor: 4.219

6.  The role of xanthine oxidase in paraquat intoxication.

Authors:  Y Kitazawa; M Matsubara; N Takeyama; T Tanaka
Journal:  Arch Biochem Biophys       Date:  1991-07       Impact factor: 4.013

Review 7.  Role of antioxidants in paraquat toxicity.

Authors:  Zacharias E Suntres
Journal:  Toxicology       Date:  2002-10-30       Impact factor: 4.221

Review 8.  Treatment of paraquat poisoning in man: methods to prevent absorption.

Authors:  T J Meredith; J A Vale
Journal:  Hum Toxicol       Date:  1987-01

Review 9.  The epidemiology and prevention of paraquat poisoning.

Authors:  L J Onyon; G N Volans
Journal:  Hum Toxicol       Date:  1987-01

10.  Efficacy of gut lavage, hemodialysis, and hemoperfusion in the therapy of paraquat or diquat intoxication.

Authors:  S Okonek; A Hofmann; B Henningsen
Journal:  Arch Toxicol       Date:  1976-09-15       Impact factor: 5.153

View more
  24 in total

1.  Protective Effects of Arachidonic Acid Against Paraquat-Induced Pulmonary Injury.

Authors:  Jianxin Du; Xia Li; CunZhi Lin; Xigang He
Journal:  Inflammation       Date:  2015-08       Impact factor: 4.092

2.  Increased plasma prothrombin time is associated with poor prognosis in patients with paraquat poisoning.

Authors:  Xiao Hu; Renyong Guo; Xing Chen; Yu Chen
Journal:  J Clin Lab Anal       Date:  2018-06-26       Impact factor: 2.352

Review 3.  Point-of-care testing in the early diagnosis of acute pesticide intoxication: The example of paraquat.

Authors:  Ting-Yen Wei; Tzung-Hai Yen; Chao-Min Cheng
Journal:  Biomicrofluidics       Date:  2018-01-19       Impact factor: 2.800

4.  Effect of acute paraquat poisoning on CYP450 isoforms activity in rats by cocktail method.

Authors:  Shuanghu Wang; Zhiyi Wang; Dongxin Chen; Mengchun Chen; Yingying Lin; Zezheng Liu; Lijing Zhang; Congcong Wen; Xianqin Wang; Jianshe Ma
Journal:  Int J Clin Exp Med       Date:  2015-10-15

5.  Tissue plasminogen activator and plasminogen activator inhibitor-1 levels in patients with acute paraquat intoxication.

Authors:  Su-Jin Seok; Su-Ji Kim; Hyo-Wook Gil; Jong-Oh Yang; Eun-Young Lee; Sae-Yong Hong
Journal:  J Korean Med Sci       Date:  2011-03-28       Impact factor: 2.153

6.  Association of the superoxide dismutase (V16A) and catalase (C262T) genetic polymorphisms with the clinical outcome of patients with acute paraquat intoxication.

Authors:  Joong-Rock Hong; Su-Jin Seok; Du-Shin Jeong; Sang-Gon Lee; Hyo-Wook Gil; Jong-Oh Yang; Eun-Young Lee; Sae-Yong Hong
Journal:  Korean J Intern Med       Date:  2010-11-27       Impact factor: 3.165

7.  Cellular toxicity of surfactants used as herbicide additives.

Authors:  Ho-Yeon Song; Young-Hee Kim; Su-Jin Seok; Hyo-Wook Gil; Jong-Oh Yang; Eun-Young Lee; Sae-Yong Hong
Journal:  J Korean Med Sci       Date:  2011-12-19       Impact factor: 2.153

8.  Common Pesticides Used in Suicide Attempts Following the 2012 Paraquat Ban in Korea.

Authors:  Jung-Won Lee; Il-Woong Hwang; Jae-Wook Kim; Hyung-Jun Moon; Ki-Hwan Kim; Suyeon Park; Hyo-Wook Gil; Sae-Yong Hong
Journal:  J Korean Med Sci       Date:  2015-09-12       Impact factor: 2.153

9.  Paraquat prohibition and change in the suicide rate and methods in South Korea.

Authors:  Woojae Myung; Geung-Hee Lee; Hong-Hee Won; Maurizio Fava; David Mischoulon; Maren Nyer; Doh Kwan Kim; Jung-Yoon Heo; Hong Jin Jeon
Journal:  PLoS One       Date:  2015-06-02       Impact factor: 3.240

10.  Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats.

Authors:  Ali Nouri; Fatemeh Heibati; Esfandiar Heidarian
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2020-07-30       Impact factor: 3.000

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.