Literature DB >> 19720075

Photo-polymeriable chitosan derivative prepared by Michael reaction of chitosan and polyethylene glycol diacrylate (PEGDA).

Guiping Ma1, Xiaodan Zhang, Jing Han, Guoqiang Song, Jun Nie.   

Abstract

N-Alkyled photo-polymeriable chitosan derivative (PEGDA-CS) was synthesized by Michael reaction of chitosan and polyethylene glycol diacrylate (PEGDA) under mild reaction conditions. The chemical structure and physical properties of PEGDA-CS were characterized by FT-IR, (1)H NMR, XRD and TG techniques. The degree of substitution (DS) of PEGDA-CS could be calculated from (1)H NMR. PEGDA-CS exhibited good solubility in distilled water. XRD analysis showed that PEGDA-CS was amorphous. TG results demonstrated that thermal stability of the derivate was lower than that of chitosan. Antimicrobial test showed that PEGDA-CS had the antimicrobial activity on Escherichia coli. It could photopolymerize under ultraviolet light with 2959 as initiator.

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Year:  2009        PMID： 19720075     DOI： 10.1016/j.ijbiomac.2009.08.007

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  5 in total

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4.  Enhanced healing of rat calvarial defects with MSCs loaded on BMP-2 releasing chitosan/alginate/hydroxyapatite scaffolds.

Authors:  Xiaoning He; Yang Liu; Xue Yuan; Li Lu
Journal:  PLoS One       Date:  2014-08-01       Impact factor: 3.240

5.  Synthesis of Polyethylene Glycol Diacrylate/Acrylic Acid Nanoparticles as Nanocarriers for the Controlled Delivery of Doxorubicin to Colorectal Cancer Cells.

Authors:  Yin Yin Myat; Tanasait Ngawhirunpat; Theerasak Rojanarata; Praneet Opanasopit; Mark Bradley; Prasopchai Patrojanasophon; Chaiyakarn Pornpitchanarong
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  5 in total

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