BACKGROUND: Metabolic syndrome (MS) has been reported to be associated with an increased risk of atrial fibrillation (AF). The aim of this study was to investigate P-wave dispersion (PWD) in patients with MS. METHODS: The study population included 66 patients with MS (21 men, 45 women; mean age, 49.7 +/- 9.1 years) and 63 control subjects without MS (26 men, 37 women; mean age, 47.0 +/- 10.6 years). The diagnosis of MS was based on the National Cholesterol Education Program Adult Treatment Panel III criteria. A 12-lead electrocardiogram was recorded for each subject. The difference between maximum and minimum P-wave duration was calculated and defined as PWD. An echocardiographic examination was also performed for each subject. RESULTS: Maximum P-wave duration and PWD were found to be significantly higher in patients with MS compared with the control subjects (Maximum P-wave duration: 113.5 +/- 9.7 ms vs 101.0 +/- 8.1 ms, PWD: 37.8 +/- 7.6 vs 23.3 +/- 5.9, respectively, P < 0.001 for both). However, there was no statistically significant difference between two groups regarding minimum P-wave duration (75.6 +/- 6.9 ms vs 77.6 +/- 7.8 ms, respectively, P = 0.18). In addition, PWD was positively correlated with age, body mass index, waist circumference, systolic and diastolic blood pressure, triglyceride level, deceleration time, isovolumetric relaxation time and negatively correlated with high-density lipoprotein cholesterol level and early-to-late diastolic velocity ratio. CONCLUSION: We have shown that patients with MS have higher PWD, indicating increased risk for AF, compared to the control subjects without MS.
BACKGROUND:Metabolic syndrome (MS) has been reported to be associated with an increased risk of atrial fibrillation (AF). The aim of this study was to investigate P-wave dispersion (PWD) in patients with MS. METHODS: The study population included 66 patients with MS (21 men, 45 women; mean age, 49.7 +/- 9.1 years) and 63 control subjects without MS (26 men, 37 women; mean age, 47.0 +/- 10.6 years). The diagnosis of MS was based on the National Cholesterol Education Program Adult Treatment Panel III criteria. A 12-lead electrocardiogram was recorded for each subject. The difference between maximum and minimum P-wave duration was calculated and defined as PWD. An echocardiographic examination was also performed for each subject. RESULTS: Maximum P-wave duration and PWD were found to be significantly higher in patients with MS compared with the control subjects (Maximum P-wave duration: 113.5 +/- 9.7 ms vs 101.0 +/- 8.1 ms, PWD: 37.8 +/- 7.6 vs 23.3 +/- 5.9, respectively, P < 0.001 for both). However, there was no statistically significant difference between two groups regarding minimum P-wave duration (75.6 +/- 6.9 ms vs 77.6 +/- 7.8 ms, respectively, P = 0.18). In addition, PWD was positively correlated with age, body mass index, waist circumference, systolic and diastolic blood pressure, triglyceride level, deceleration time, isovolumetric relaxation time and negatively correlated with high-density lipoprotein cholesterol level and early-to-late diastolic velocity ratio. CONCLUSION: We have shown that patients with MS have higher PWD, indicating increased risk for AF, compared to the control subjects without MS.
Authors: Vincenzo Russo; Anna Rago; Bruno Pannone; Federica Di Meo; Andrea Antonio Papa; Maria Carolina Mayer; Anna Spasiano; Maria Giovanna Russo; Paolo Golino; Raffaele Calabrò; Gerardo Nigro Journal: Int J Hematol Date: 2011-03-10 Impact factor: 2.490
Authors: Rikki M Tanner; Usman Baber; April P Carson; Jenifer Voeks; Todd M Brown; Elsayed Z Soliman; Virginia J Howard; Paul Muntner Journal: Am J Cardiol Date: 2011-04-29 Impact factor: 2.778
Authors: Hale Yilmaz; Kazım Serhan Özcan; Nurten Sayar; Tugba Kemaloglu; Baris Gungor; Betul Erer; Mehmet Yilmaz; Ufuk Gurkan; Nazmiye Cakmak; Dilaver Oz; Ali Nazmi Calik; Osman Bolca Journal: Med Princ Pract Date: 2015-01-10 Impact factor: 1.927
Authors: Vincenzo Russo; Anna Rago; Bruno Pannone; Andrea Antonio Papa; Maria Carolina Mayer; Anna Spasiano; Raffaele Calabro; Maria Giovanna Russo; Nigro Gerardo Journal: Indian Pacing Electrophysiol J Date: 2014-05-25