Literature DB >> 19718411

Cholesterol granuloma of the tympanic membrane presenting as a blue eardrum.

Chul Ho Jang1, Jun Sung Kim, Yong Bum Cho.   

Abstract

Intramembranous tympanic membrane cholesterol granuloma (CG) occurs infrequently. Here, the authors report a case of CG in the tympanic membrane presenting as a blue eardrum in the right ear. In addition, a pinhole perforation noted in the anterosuperior area revealed a brown discharge. High-resolution temporal bone CT showed a bulging mass shadow in the middle ear and a soft tissue dense lesion that filled both the epitympanum and mastoid cavity. Tympanomastoidectomy was performed under general anesthesia. New bone formation was confirmed in the mastoid antrum and epitympanum, and the epitympanum was blocked by new bone. The tympanic membrane revealed a round, brownish mass with a glistening surface and a severely thickened pars tensa. We herein report this case and review pertinent medical literature.

Entities:  

Keywords:  Cholesterol granuloma; tympanic membrane

Mesh:

Substances:

Year:  2009        PMID: 19718411      PMCID: PMC2730625          DOI: 10.3349/ymj.2009.50.4.585

Source DB:  PubMed          Journal:  Yonsei Med J        ISSN: 0513-5796            Impact factor:   2.759


  12 in total

1.  Incidental petrous apex findings on magnetic resonance imaging.

Authors:  J P Leonetti; H Shownkeen; S J Marzo
Journal:  Ear Nose Throat J       Date:  2001-04       Impact factor: 1.697

2.  Temporal bone histopathology in chronically infected ears with intact and perforated tympanic membranes.

Authors:  S S da Costa; M M Paparella; P A Schachern; T H Yoon; B P Kimberley
Journal:  Laryngoscope       Date:  1992-11       Impact factor: 3.325

3.  Histopathologic study of the temporal bones and Eustachian tubes of children with cholesterol granuloma.

Authors:  Makoto Miura; Isamu Sando; Yorihisa Orita; Barry E Hirsch
Journal:  Ann Otol Rhinol Laryngol       Date:  2002-07       Impact factor: 1.547

4.  Cholesterol granuloma in the tympanic membrane.

Authors:  Shin-Ichi Haginomori; Atsuko Takamaki; Kanako Ito; Hiroshi Takenaka; Yoshitaka Kurisu; Motomu Tsuji
Journal:  Otol Neurotol       Date:  2006-12       Impact factor: 2.311

5.  Cholesterol granuloma presenting in the ear canal.

Authors:  B H Matt; C M Myer; P S Bellet
Journal:  Ann Otol Rhinol Laryngol       Date:  1990-08       Impact factor: 1.547

6.  Cholesterol cyst manifesting as a middle ear vascular tumor.

Authors:  R A Hoffman
Journal:  Am J Otolaryngol       Date:  1984 Jan-Feb       Impact factor: 1.808

7.  Cholesterol granuloma involving the temporal bone.

Authors:  G T Nager; T S Vanderveen
Journal:  Ann Otol Rhinol Laryngol       Date:  1976 Mar-Apr       Impact factor: 1.547

8.  Surgical management of petrous apex cholesterol granulomas.

Authors:  Derald E Brackmann; Elizabeth H Toh
Journal:  Otol Neurotol       Date:  2002-07       Impact factor: 2.311

9.  Large cholesterol granuloma cysts in the mastoid. Clinical and histopathologic findings.

Authors:  T Palva; V P Lehto; L G Johnsson; I Virtanen; J Mäkinen
Journal:  Arch Otolaryngol       Date:  1985-12

10.  A new theory to explain the genesis of petrous apex cholesterol granuloma.

Authors:  Robert K Jackler; Michael Cho
Journal:  Otol Neurotol       Date:  2003-01       Impact factor: 2.311

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  1 in total

1.  Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse.

Authors:  Konrad Noben-Trauth; Joseph R Latoche
Journal:  J Biol Chem       Date:  2010-11-09       Impact factor: 5.157

  1 in total

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