OBJECTIVES: To apply autologous Plasma Rich in Growth Factors (PRGF) in wounds provoked in the tongue of New Zealand albino rabbits and to study its effects in the epithelialization and inflammation of the wounds at 7 and 28 days after its application. STUDY DESIGN: A prospective study carried out on 20 adult rabbits. Two wounds were made on the midline of the dorsal surface of the tongue in each animal, one control, and the other in which PRGF was applied. A histological study of the epithelialization and inflammation of wounds at 7 and 28 days was made. RESULTS: At 7 days were not observed differences between the study group and the control, nevertheless at 28 days all the wounds in which we applied the PRGF were completely epithelialized and with resolution of the inflammatory process, finding significant differences with respect to the control (p=0.031) and (p=0.023). CONCLUSIONS: The PRGF accelerates epithelialization and reduces inflammation at 28 days of provoking wounds in the oral mucosa.
OBJECTIVES: To apply autologous Plasma Rich in Growth Factors (PRGF) in wounds provoked in the tongue of New Zealand albino rabbits and to study its effects in the epithelialization and inflammation of the wounds at 7 and 28 days after its application. STUDY DESIGN: A prospective study carried out on 20 adult rabbits. Two wounds were made on the midline of the dorsal surface of the tongue in each animal, one control, and the other in which PRGF was applied. A histological study of the epithelialization and inflammation of wounds at 7 and 28 days was made. RESULTS: At 7 days were not observed differences between the study group and the control, nevertheless at 28 days all the wounds in which we applied the PRGF were completely epithelialized and with resolution of the inflammatory process, finding significant differences with respect to the control (p=0.031) and (p=0.023). CONCLUSIONS: The PRGF accelerates epithelialization and reduces inflammation at 28 days of provoking wounds in the oral mucosa.
Authors: Syed Sarim Imam; Fahad A Al-Abbasi; Salman Hosawi; Muhammad Afzal; Muhammad Shahid Nadeem; Mohammed M Ghoneim; Sultan Alshehri; Sami I Alzarea; Ali Alquraini; Gaurav Gupta; Imran Kazmi Journal: Regen Ther Date: 2022-02-15 Impact factor: 3.419
Authors: Deborah Chicharro; Jose M Carrillo; Mónica Rubio; Ramón Cugat; Belén Cuervo; Silvia Guil; Jerónimo Forteza; Victoria Moreno; Jose M Vilar; Joaquín Sopena Journal: BMC Vet Res Date: 2018-09-21 Impact factor: 2.741