Literature DB >> 19716140

Endobronchial tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis.

Christian Schumann1, Martin Hetzel, Alexander J Babiak, Jürgen Hetzel, Tobias Merk, Thomas Wibmer, Philipp M Lepper, Stefan Krüger.   

Abstract

OBJECTIVE: In addition to use of a laser, argon plasma coagulation, electrocautery, or coring with a rigid bronchoscope, tumor debulking with a flexible cryoprobe is used for therapeutic bronchoscopy with an immediate effect for endobronchial pathologies. We performed this analysis to determine the usefulness, efficacy, and safety of the flexible cryorecanalization in a large population under routine conditions.
METHODS: We identified 225 bronchoscopic interventions that were done as cryorecanalization with a flexible cryoprobe. All patients had symptomatic airway stenosis. We determined the endoscopic success rate and safety (bleeding and perforation) of the procedure.
RESULTS: Successful cryorecanalization was achieved in 205 (91.1%) of 225 patients. The flexible cryoprobe was used with all patients, in most patients in combination with flexible bronchoscopy and only in a minority (n = 31, 13.8%) in combination with a rigid bronchoscope. Additional interventional techniques used were endobronchial stents (n = 11, 4.9%) and argon plasma coagulation (n = 37, 16.4%). Mild bleeding (if ice-cold NaCl or epinephrine solution was necessary) occurred in 9 (4.0%) patients, moderate bleeding (if argon plasma coagulation or a bronchus blocker was required) occurred in 18 (8.0%) patients, and severe bleeding (events with hemodynamic instability) never occurred.
CONCLUSIONS: Cryorecanalization with the flexible cryoprobe for treatment of symptomatic endobronchial tumor stenosis is a safe technique with a high success rate and immediate treatment effect. Copyright 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Mesh:

Year:  2009        PMID: 19716140     DOI: 10.1016/j.jtcvs.2009.06.023

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  34 in total

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Authors:  Philip G Ong; Labib G Debiane; Roberto F Casal
Journal:  J Thorac Dis       Date:  2016-12       Impact factor: 2.895

2.  Endoscopic cryosurgical resection of pulmonary hamartoma with flexible bronchoscopy.

Authors:  Sung Ho Lee; Kwang-Taik Kim; Eun Jue Yi; Jin-Sung Son
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2011-08-18

3.  Endoscopic management of benign tracheobronchial tumors.

Authors:  Hui Gao; Xin Ding; Dong Wei; Peng Cheng; Xiaomei Su; Huanyi Liu; Tao Zhang
Journal:  J Thorac Dis       Date:  2011-12       Impact factor: 2.895

4.  Spray cryotherapy is effective for bronchoscopic, endoscopic and open ablation of thoracic tissues.

Authors:  Joyce T Au; Joshua Carson; Sebastien Monette; David J Finley
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-07-18

5.  How many samples would be optimal for endobronchial cryobiopsy?

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Review 6.  [Endoscopic interventions in pulmonology].

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7.  Adjuvant treatment of proper endobronchial management in leiomyosarcoma.

Authors:  Soo Jung Kim; Junghyun Kim; Ju-Hee Park; Ae-Ra Lee; Jung-Kyu Lee; Tae Min Kim; Young Sik Park
Journal:  Tuberc Respir Dis (Seoul)       Date:  2013-12-24

8.  An Open-label, Single-arm Study of CRYO2 for Debulking at the Site of Central Airway Obstruction or Stenosis.

Authors:  Hideo Saka; Masahide Oki; Akiko Kada; Akiko M Saito
Journal:  In Vivo       Date:  2019 Sep-Oct       Impact factor: 2.155

9.  Cryorecanalization: keys to success.

Authors:  Aydin Yilmaz; Zafer Aktaş; Ibrahim Onur Alici; Atalay Cağlar; Hilal Sazak; Fatma Ulus
Journal:  Surg Endosc       Date:  2012-05-19       Impact factor: 4.584

Review 10.  Malignant central airway obstruction.

Authors:  Lakshmi Mudambi; Russell Miller; George A Eapen
Journal:  J Thorac Dis       Date:  2017-09       Impact factor: 2.895

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