Literature DB >> 19715585

Customized pachymetric guided epithelial debridement for corneal collagen cross linking.

George D Kymionis1, Vasilios F Diakonis, Efekan Coskunseven, Mirco Jankov, Sonia H Yoo, Ioannis G Pallikaris.   

Abstract

BACKGROUND: We describe a modified method for deepitheliazation prior to corneal cross linking (CXL). The technique may overcome the current corneal pachymetric limitation parameter (over 400 microns) that is necessary for the safety of the procedure without affecting the overall benefits.
METHODS: In a series of two patients, with inferior topographic steepening and regional thinning (less than 400 microns corresponding to the area of corneal steepening), CXL after customized epithelial removal was performed.
RESULTS: There were no intra- or postoperative adverse events seen by the nine month follow up examination. Stabilization of the corneal ectasia was observed up to nine months post-costumized pachymetric-guided epithelial removal.
CONCLUSION: The technique of customized pachymetric-guided epithelial removal is easy to perform and may overcome the limitations of the preoperative corneal pachymetry expanding the application of the procedure in patients with regional corneal thinning.

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Year:  2009        PMID: 19715585      PMCID: PMC2744909          DOI: 10.1186/1471-2415-9-10

Source DB:  PubMed          Journal:  BMC Ophthalmol        ISSN: 1471-2415            Impact factor:   2.209


  9 in total

1.  UV absorbance of the human cornea in the 240- to 400-nm range.

Authors:  Lajos Kolozsvári; Antal Nógrádi; Béla Hopp; Zsolt Bor
Journal:  Invest Ophthalmol Vis Sci       Date:  2002-07       Impact factor: 4.799

2.  Increased resistance of crosslinked cornea against enzymatic digestion.

Authors:  Eberhard Spoerl; Gregor Wollensak; Theo Seiler
Journal:  Curr Eye Res       Date:  2004-07       Impact factor: 2.424

3.  Corneal cross-linking-induced stromal demarcation line.

Authors:  Theo Seiler; Farhad Hafezi
Journal:  Cornea       Date:  2006-10       Impact factor: 2.651

Review 4.  Safety of UVA-riboflavin cross-linking of the cornea.

Authors:  Eberhard Spoerl; Michael Mrochen; David Sliney; Stephen Trokel; Theo Seiler
Journal:  Cornea       Date:  2007-05       Impact factor: 2.651

Review 5.  [Therapeutic cross-linking of the cornea using riboflavin/UVA].

Authors:  T Koller; T Seiler
Journal:  Klin Monbl Augenheilkd       Date:  2007-09       Impact factor: 0.700

6.  Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus.

Authors:  Gregor Wollensak; Eberhard Spoerl; Theo Seiler
Journal:  Am J Ophthalmol       Date:  2003-05       Impact factor: 5.258

7.  Corneal endothelial cytotoxicity of riboflavin/UVA treatment in vitro.

Authors:  Gregor Wollensak; Eberhard Spörl; Friedemann Reber; Lutz Pillunat; Richard Funk
Journal:  Ophthalmic Res       Date:  2003 Nov-Dec       Impact factor: 2.892

8.  Keratocyte cytotoxicity of riboflavin/UVA-treatment in vitro.

Authors:  G Wollensak; E Spoerl; F Reber; T Seiler
Journal:  Eye (Lond)       Date:  2004-07       Impact factor: 3.775

9.  Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis.

Authors:  Farhad Hafezi; John Kanellopoulos; Rainer Wiltfang; Theo Seiler
Journal:  J Cataract Refract Surg       Date:  2007-12       Impact factor: 3.351

  9 in total
  19 in total

1.  Brillouin microscopy of collagen crosslinking: noncontact depth-dependent analysis of corneal elastic modulus.

Authors:  Giuliano Scarcelli; Sabine Kling; Elena Quijano; Roberto Pineda; Susana Marcos; Seok Hyun Yun
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-02-19       Impact factor: 4.799

2.  Outcomes of corneal collagen crosslinking using a customized epithelial debridement technique in keratoconic eyes with thin corneas.

Authors:  Nurullah Cagil; Ozge Sarac; Gamze Dereli Can; Emine Akcay; Mehmet Erol Can
Journal:  Int Ophthalmol       Date:  2016-04-21       Impact factor: 2.031

3.  Long-term visual, refractive, tomographic and aberrometric outcomes of corneal collagen crosslinking (CXL) with or without hypoosmolar riboflavin solution in the treatment of progressive keratoconus patients with thin corneas.

Authors:  Tuna Celik Buyuktepe; Omur O Ucakhan
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-11-27       Impact factor: 3.117

4.  Depth-Dependent Reduction of Biomechanical Efficacy of Contact Lens-Assisted Corneal Cross-linking Analyzed by Brillouin Microscopy.

Authors:  Hongyuan Zhang; Mehdi Roozbahani; Andre L Piccinini; Oren Golan; Farhad Hafezi; Giuliano Scarcelli; J Bradley Randleman
Journal:  J Refract Surg       Date:  2019-11-01       Impact factor: 3.573

5.  Collagen cross-linking: current status and future directions.

Authors:  Marine Hovakimyan; Rudolf F Guthoff; Oliver Stachs
Journal:  J Ophthalmol       Date:  2012-01-12       Impact factor: 1.909

6.  Late Stage of Corneal Decompensation Caused by Progressive Keratoconus: Can We Treat It and Save the Cornea?

Authors:  Igor Knezović; Mirna Belovari Višnjić; Hrvoje Raguž
Journal:  Case Rep Ophthalmol Med       Date:  2015-04-30

7.  Safety and Efficacy of Epithelial Island Crosslinking in Keratoconus with Thinnest Pachymetry less than 400µ.

Authors:  Hisham A Omar; Mohamed-Sameh H El-Agha; Mohamed A Hassaballah; Noha M Khalil
Journal:  Middle East Afr J Ophthalmol       Date:  2021-04-30

8.  Transepithelial corneal collagen cross-linking in ultrathin keratoconic corneas.

Authors:  Leopoldo Spadea; Rita Mencucci
Journal:  Clin Ophthalmol       Date:  2012-11-02

Review 9.  Corneal collagen cross-linking (CXL) in thin corneas.

Authors:  Xiangjun Chen; Aleksandar Stojanovic; Jon Roger Eidet; Tor Paaske Utheim
Journal:  Eye Vis (Lond)       Date:  2015-09-07

Review 10.  Collagen cross-linking in thin corneas.

Authors:  Prema Padmanabhan; Abhishek Dave
Journal:  Indian J Ophthalmol       Date:  2013-08       Impact factor: 1.848

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