| Literature DB >> 19714266 |
Gary J Bennett1, C Peter N Watson.
Abstract
OBJECTIVES: The history behind the current understanding of the varicella-zoster virus and its relationship to the pain conditions caused by shingles and postherpetic neuralgia are reviewed. The framework for the current conceptualization is Hope-Simpson's latency hypothesis. Data from recent work in virology, neuroanatomy and epidemiology are reviewed, as is work using varicella-zoster virus-infected animals. The recent data largely confirm Hope-Simpson's hypothesis and extend it significantly.Entities:
Mesh:
Year: 2009 PMID: 19714266 PMCID: PMC2734513 DOI: 10.1155/2009/380384
Source DB: PubMed Journal: Pain Res Manag ISSN: 1203-6765 Impact factor: 3.037