| Literature DB >> 19713983 |
Richard M Goldberg, Bert H O'Neil.
Abstract
The optimal therapy for patients with metastatic and treatment-refractory colorectal cancer is controversial. Questions with regard to both the sequence and combinations of different drugs need to be answered by well-designed and adequately powered studies before the most appropriate option for second-line treatment for these patients can be defined.Entities:
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Year: 2009 PMID： 19713983 DOI： 10.1038/nrgastro.2009.140
Source DB: PubMed Journal: Nat Rev Gastroenterol Hepatol ISSN： 1759-5045 Impact factor: 46.802