| Literature DB >> 19713078 |
Luigi D'Argenzio1, Giacomo Koch, Roberta Bombardieri, Francesco Mori, Romina Moavero, Diego Centonze, Paolo Curatolo.
Abstract
Abnormal connectivity might be involved in the pathophysiology of Tuberous Sclerosis Complex (TSC). We used twin-coil Transcranial Magnetic Stimulation protocol to investigate connectivity between posterior parietal cortex (PPC) and motor cortex (M1) in TSC patients. In comparison with healthy subjects and TSC patients treated with antiepileptic drugs, non-medicated TSC patients exhibited abnormal excitability of PPC-M1 connection. Such altered connectivity might play a role in TSC epileptic phenotype. 2009 Elsevier B.V. All rights reserved.Entities:
Mesh：
Year: 2009 PMID： 19713078 DOI： 10.1016/j.eplepsyres.2009.07.009
Source DB: PubMed Journal: Epilepsy Res ISSN： 0920-1211 Impact factor: 3.045