Literature DB >> 19712586

Anti-oxidative effects of Phellinus linteus and red ginseng extracts on oxidative stress-induced DNA damage.

Byung-Jae Park1, Yeong-Seok Lim, Hee-Jung Lee, Won Sik Eum, Jinseu Park, Kyu Hyung Han, Soo Young Choi, Kil Soo Lee.   

Abstract

Anti-oxidative effect of Phellinus linteus (P. linteus) and red ginseng extracts on DNA damage induced by reactive oxygen species (ROS) were investigated in this study. P. linteus (PLE) and red ginseng extracts (RGE) inhibited the breaking of E. coli ColE1 plasmid DNA strands as well as nuclear DNA of rat hepatocytes damaged by oxidative stress. In addition, a reaction mixture of PLE and RGE showed synergistic inhibitory effect against DNA damage. These results suggest that PLE and RGE have a cellular defensive effect against DNA damage induced by ROS.

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Year:  2009        PMID： 19712586     DOI： 10.5483/bmbrep.2009.42.8.500

Source DB:  PubMed          Journal:  BMB Rep        ISSN： 1976-6696            Impact factor:   4.778


  13 in total

1.  Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.

Authors:  Nigar Fatma; Prerna Singh; Bhavana Chhunchha; Eri Kubo; T Shinohara; Biju Bhargavan; Dhirendra P Singh
Journal:  Am J Physiol Cell Physiol       Date:  2011-06-15       Impact factor: 4.249

2.  Red ginseng deregulates hypoxia-induced genes by dissociating the HIF-1 dimer.

Authors:  Yong-Joon Choi; Hyunsung Choi; Chung-Hyun Cho; Jong-Wan Park
Journal:  J Nat Med       Date:  2011-01-18       Impact factor: 2.343

3.  Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a randomized, double-blind, placebo-controlled trial.

Authors:  Ji Young Kim; Ju Yeon Park; Hee Jung Kang; Oh Yoen Kim; Jong Ho Lee
Journal:  Nutr J       Date:  2012-07-17       Impact factor: 3.271

4.  Korean red ginseng water extract restores impaired endothelial function by inhibiting arginase activity in aged mice.

Authors:  Kwanhoon Choi; Jeongyeon Yoon; Hyun Kyo Lim; Sungwoo Ryoo
Journal:  Korean J Physiol Pharmacol       Date:  2014-04-03       Impact factor: 2.016

Review 5.  Implications of red Panax ginseng in oxidative stress associated chronic diseases.

Authors:  Yoon-Mi Lee; Haelim Yoon; Hyun-Min Park; Byeng Chun Song; Kyung-Jin Yeum
Journal:  J Ginseng Res       Date:  2016-03-10       Impact factor: 6.060

6.  Up-regulation of Heme Oxygenase-1 by Korean Red Ginseng Water Extract as a Cytoprotective Effect in Human Endothelial Cells.

Authors:  Hana Yang; Seung Eun Lee; Seong Il Jeong; Cheung-Seog Park; Young-Ho Jin; Yong Seek Park
Journal:  J Ginseng Res       Date:  2011-09       Impact factor: 6.060

7.  Korean red ginseng inhibits arginase and contributes to endotheliumdependent vasorelaxation through endothelial nitric oxide synthase coupling.

Authors:  Woosung Shin; Jeongyeon Yoon; Goo Taeg Oh; Sungwoo Ryoo
Journal:  J Ginseng Res       Date:  2013-03       Impact factor: 6.060

8.  Korean Red Ginseng water extract inhibits COX-2 expression by suppressing p38 in acrolein-treated human endothelial cells.

Authors:  Seung Eun Lee; Yong Seek Park
Journal:  J Ginseng Res       Date:  2013-12-08       Impact factor: 6.060

9.  Effect of Korean Red Ginseng treatment on the gene expression profile of diabetic rat retina.

Authors:  Hana Yang; Gun Woo Son; Hye Rim Park; Seung Eun Lee; Yong Seek Park
Journal:  J Ginseng Res       Date:  2015-03-14       Impact factor: 6.060

10.  Red ginseng marc oil inhibits iNOS and COX-2 via NFκB and p38 pathways in LPS-stimulated RAW 264.7 macrophages.

Authors:  Min-Ji Bak; Soon-Gi Hong; Jong-Won Lee; Woo-Sik Jeong
Journal:  Molecules       Date:  2012-11-22       Impact factor: 4.411
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