Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tuberculous meningitis.

Literature DB >> 19712035

Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tuberculous meningitis.

J W C Alffenaar¹, R van Altena, H J Bökkerink, G J Luijckx, D van Soolingen, R E Aarnoutse, T S van der Werf.

Abstract

Moxifloxacin cerebrospinal fluid (CSF) penetration was evaluated by obtaining full plasma and CSF time concentration curves for 4 patients with tuberculous meningitis. The geometric mean ratio of the areas under the curve for CSF to plasma were 0.82 (range, 0.70-0.94) at 400 mg once per day and 0.71 (0.58-0.84) at 800 mg once per day.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2009 PMID： 19712035 DOI： 10.1086/605576

Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079

Keyword Cloud
Cited

30 in total

1. Rapid drug tolerance and dramatic sterilizing effect of moxifloxacin monotherapy in a novel hollow-fiber model of intracellular Mycobacterium kansasii disease.

Authors: Shashikant Srivastava; Jotam Pasipanodya; Carleton M Sherman; Claudia Meek; Richard Leff; Tawanda Gumbo
Journal: Antimicrob Agents Chemother Date: 2015-02-02 Impact factor: 5.191

2. Approach to the diagnosis and management of tuberculous meningitis.

Authors: Scott W Sinner
Journal: Curr Infect Dis Rep Date: 2010-07 Impact factor: 3.725

3. Trimethoprim/Sulfamethoxazole and Moxifloxacin Therapy for a Pediatric Stenotrophomonas Maltophilia Ventriculoperitoneal Shunt Infection.

Authors: Eric R Gregory; Sam B Osborne; Brian M Gardner; Robert A Broughton
Journal: J Pediatr Pharmacol Ther Date: 2019 Jan-Feb

4. Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid.

Authors: Marija Djukic; Martin Munz; Fritz Sörgel; Ulrike Holzgrabe; Helmut Eiffert; Roland Nau
Journal: Antimicrob Agents Chemother Date: 2011-11-21 Impact factor: 5.191

Review 5. Targeting multidrug-resistant tuberculosis (MDR-TB) by therapeutic vaccines.

Authors: Satria A Prabowo; Matthias I Gröschel; Ed D L Schmidt; Alena Skrahina; Traian Mihaescu; Serap Hastürk; Rotislav Mitrofanov; Edita Pimkina; Ildikó Visontai; Bouke de Jong; John L Stanford; Père-Joan Cardona; Stefan H E Kaufmann; Tjip S van der Werf
Journal: Med Microbiol Immunol Date: 2012-11-10 Impact factor: 3.402

Pharmacokinetics of moxifloxacin in cerebrospinal fluid and plasma in patients with tuberculous meningitis.

1. Rapid drug tolerance and dramatic sterilizing effect of moxifloxacin monotherapy in a novel hollow-fiber model of intracellular Mycobacterium kansasii disease.

2. Approach to the diagnosis and management of tuberculous meningitis.

3. Trimethoprim/Sulfamethoxazole and Moxifloxacin Therapy for a Pediatric Stenotrophomonas Maltophilia Ventriculoperitoneal Shunt Infection.

4. Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid.

Review 5. Targeting multidrug-resistant tuberculosis (MDR-TB) by therapeutic vaccines.

6. Life-threatening disseminated tuberculosis as a complication of TNF-α blockade in an adolescent.

7. Septic cavernous sinus thrombosis caused by tuberculosis infection.

Review 8. A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis.

Review 9. Pharmacokinetic and Pharmacodynamic Principles of Anti-infective Dosing.

Review 10. Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.