Literature DB >> 19712002

The future of molecular approaches to inflammatory bowel disease.

Boyko Kabakchiev1, Smita Halder, Mark S Silverberg.   

Abstract

Technological advances in genomics and transcriptomics have resulted in the introduction of molecular tests into the clinical arena. Despite established uses of such tests in the oncology field, their integration into the management of complex diseases has not been widely evaluated. Progress in the field of inflammatory bowel disease (IBD) genetics has been rapid in recent years, and these advances have provided more urgent impetus to investigating the role of molecular tests in IBD. This article summarizes the current state of molecular testing available for IBD, and the potential utility of such tests as research in the area widens.

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Year:  2009        PMID： 19712002     DOI： 10.1007/BF03256328

Source DB:  PubMed          Journal:  Mol Diagn Ther        ISSN： 1177-1062            Impact factor:   4.074


  70 in total

1.  Protein microarray analysis of disease activity in pediatric inflammatory bowel disease demonstrates elevated serum PLGF, IL-7, TGF-beta1, and IL-12p40 levels in Crohn's disease and ulcerative colitis patients in remission versus active disease.

Authors:  Howard A Kader; Velizar T Tchernev; Ebenezer Satyaraj; Serguei Lejnine; Gregory Kotler; Stephen F Kingsmore; Dhavalkumar D Patel
Journal:  Am J Gastroenterol       Date:  2005-02       Impact factor: 10.864

2.  Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology.

Authors:  Mark S Silverberg; Jack Satsangi; Tariq Ahmad; Ian D R Arnott; Charles N Bernstein; Steven R Brant; Renzo Caprilli; Jean-Frédéric Colombel; Christoph Gasche; Karel Geboes; Derek P Jewell; Amir Karban; Edward V Loftus; A Salvador Peña; Robert H Riddell; David B Sachar; Stefan Schreiber; A Hillary Steinhart; Stephan R Targan; Severine Vermeire; B F Warren
Journal:  Can J Gastroenterol       Date:  2005-09       Impact factor: 3.522

3.  The epidemiology of inflammatory bowel disease in Canada: a population-based study.

Authors:  Charles N Bernstein; Andre Wajda; Lawrence W Svenson; Adrian MacKenzie; Mieke Koehoorn; Maureen Jackson; Richard Fedorak; David Israel; James F Blanchard
Journal:  Am J Gastroenterol       Date:  2006-07       Impact factor: 10.864

4.  Inflammatory gene signature in ulcerative colitis with cDNA macroarray analysis.

Authors:  S Okahara; Y Arimura; T Yabana; K Kobayashi; A Gotoh; S Motoya; A Imamura; T Endo; K Imai
Journal:  Aliment Pharmacol Ther       Date:  2005-05-01       Impact factor: 8.171

5.  CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease.

Authors:  Suzanne Lesage; Habib Zouali; Jean-Pierre Cézard; Jean-Frédéric Colombel; Jacques Belaiche; Sven Almer; Curt Tysk; Colm O'Morain; Miquel Gassull; Vibeke Binder; Yigael Finkel; Robert Modigliani; Corinne Gower-Rousseau; Jeanne Macry; Françoise Merlin; Mathias Chamaillard; Anne-Sophie Jannot; Gilles Thomas; Jean-Pierre Hugot
Journal:  Am J Hum Genet       Date:  2002-03-01       Impact factor: 11.025

6.  Innate immune receptor genetic polymorphisms in pouchitis: is CARD15 a susceptibility factor?

Authors:  Carmen B Meier; Refaat A Hegazi; James Aisenberg; Peter E Legnani; Naris Nilubol; Gena M Cobrin; Richard H Duerr; Stephen R Gorfine; Joel J Bauer; David B Sachar; Scott E Plevy
Journal:  Inflamm Bowel Dis       Date:  2005-11       Impact factor: 5.325

7.  From model cell line to in vivo gene expression: disease-related intestinal gene expression in IBD.

Authors:  H A Schulze; R Häsler; N Mah; T Lu; S Nikolaus; C M Costello; S Schreiber
Journal:  Genes Immun       Date:  2008-03-13       Impact factor: 2.676

Review 8.  C-reactive protein as a marker for inflammatory bowel disease.

Authors:  Séverine Vermeire; Gert Van Assche; Paul Rutgeerts
Journal:  Inflamm Bowel Dis       Date:  2004-09       Impact factor: 5.325

9.  Multigene analysis can discriminate between ulcerative colitis, Crohn's disease, and irritable bowel syndrome.

Authors:  Petra von Stein; Robert Lofberg; Nikolai V Kuznetsov; Alexander W Gielen; Jan-Olov Persson; Rolf Sundberg; Karin Hellstrom; Anders Eriksson; Ragnar Befrits; Ake Ost; Oliver D von Stein
Journal:  Gastroenterology       Date:  2008-03-02       Impact factor: 22.682

10.  Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays.

Authors:  Christine M Costello; Nancy Mah; Robert Häsler; Philip Rosenstiel; Georg H Waetzig; Andreas Hahn; Tim Lu; Yesim Gurbuz; Susanna Nikolaus; Mario Albrecht; Jochen Hampe; Ralph Lucius; Günther Klöppel; Holger Eickhoff; Hans Lehrach; Thomas Lengauer; Stefan Schreiber
Journal:  PLoS Med       Date:  2005-08-23       Impact factor: 11.069
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  1 in total

Review 1.  Have genomic discoveries in inflammatory bowel disease translated into clinical progress?

Authors:  Adam V Weizman; Mark S Silverberg
Journal:  Curr Gastroenterol Rep       Date:  2012-04
  1 in total

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