Literature DB >> 19710632

Changing fear: the neurocircuitry of emotion regulation.

Catherine A Hartley1, Elizabeth A Phelps.   

Abstract

The ability to alter emotional responses as circumstances change is a critical component of normal adaptive behavior and is often impaired in psychological disorders. In this review, we discuss four emotional regulation techniques that have been investigated as means to control fear: extinction, cognitive regulation, active coping, and reconsolidation. For each technique, we review what is known about the underlying neural systems, combining findings from animal models and human neuroscience. The current evidence suggests that these different means of regulating fear depend on both overlapping and distinct components of a fear circuitry.

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Year:  2010        PMID: 19710632      PMCID: PMC3055445          DOI: 10.1038/npp.2009.121

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN: 0893-133X            Impact factor:   7.853


  91 in total

1.  Neural correlates of conscious self-regulation of emotion.

Authors:  M Beauregard; J Lévesque; P Bourgouin
Journal:  J Neurosci       Date:  2001-09-15       Impact factor: 6.167

2.  Electrical stimulation of medial prefrontal cortex reduces conditioned fear in a temporally specific manner.

Authors:  M R Milad; I Vidal-Gonzalez; G J Quirk
Journal:  Behav Neurosci       Date:  2004-04       Impact factor: 1.912

3.  Factors regulating the effects of hippocampal inactivation on renewal of conditional fear after extinction.

Authors:  Kevin A Corcoran; Stephen Maren
Journal:  Learn Mem       Date:  2004 Sep-Oct       Impact factor: 2.460

Review 4.  Amygdala, medial prefrontal cortex, and hippocampal function in PTSD.

Authors:  Lisa M Shin; Scott L Rauch; Roger K Pitman
Journal:  Ann N Y Acad Sci       Date:  2006-07       Impact factor: 5.691

Review 5.  A framework for studying the neurobiology of value-based decision making.

Authors:  Antonio Rangel; Colin Camerer; P Read Montague
Journal:  Nat Rev Neurosci       Date:  2008-06-11       Impact factor: 34.870

Review 6.  Clinical implications of neuroscience research in PTSD.

Authors:  Bessel A van der Kolk
Journal:  Ann N Y Acad Sci       Date:  2006-07       Impact factor: 5.691

7.  Prefrontal infusion of PD098059 immediately after fear extinction training blocks extinction-associated prefrontal synaptic plasticity and decreases prefrontal ERK2 phosphorylation.

Authors:  Sandrine Hugues; Aline Chessel; Isabelle Lena; Robert Marsault; Rene Garcia
Journal:  Synapse       Date:  2006-09-15       Impact factor: 2.562

8.  Neurons in medial prefrontal cortex signal memory for fear extinction.

Authors:  Mohammed R Milad; Gregory J Quirk
Journal:  Nature       Date:  2002-11-07       Impact factor: 49.962

9.  Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats.

Authors:  David L Walker; Kerry J Ressler; Kwok-Tung Lu; Michael Davis
Journal:  J Neurosci       Date:  2002-03-15       Impact factor: 6.167

Review 10.  Traumatic stress: effects on the brain.

Authors:  J Douglas Bremner
Journal:  Dialogues Clin Neurosci       Date:  2006       Impact factor: 5.986

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  183 in total

Review 1.  Pharmacological enhancement of drug cue extinction learning: translational challenges.

Authors:  K M Kantak; B Á Nic Dhonnchadha
Journal:  Ann N Y Acad Sci       Date:  2011-01       Impact factor: 5.691

Review 2.  Neural and cellular mechanisms of fear and extinction memory formation.

Authors:  Caitlin A Orsini; Stephen Maren
Journal:  Neurosci Biobehav Rev       Date:  2012-01-02       Impact factor: 8.989

3.  Emotion regulation reduces loss aversion and decreases amygdala responses to losses.

Authors:  Peter Sokol-Hessner; Colin F Camerer; Elizabeth A Phelps
Journal:  Soc Cogn Affect Neurosci       Date:  2012-01-24       Impact factor: 3.436

4.  Overlapping neural substrates between intentional and incidental down-regulation of negative emotions.

Authors:  Doris E Payer; Kate Baicy; Matthew D Lieberman; Edythe D London
Journal:  Emotion       Date:  2012-04

5.  Exposure therapy triggers lasting reorganization of neural fear processing.

Authors:  Katherina K Hauner; Susan Mineka; Joel L Voss; Ken A Paller
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-23       Impact factor: 11.205

6.  Functional network dysfunction in anxiety and anxiety disorders.

Authors:  C M Sylvester; M Corbetta; M E Raichle; T L Rodebaugh; B L Schlaggar; Y I Sheline; C F Zorumski; E J Lenze
Journal:  Trends Neurosci       Date:  2012-06-02       Impact factor: 13.837

Review 7.  The neuroscience of race.

Authors:  Jennifer T Kubota; Mahzarin R Banaji; Elizabeth A Phelps
Journal:  Nat Neurosci       Date:  2012-06-26       Impact factor: 24.884

Review 8.  Stress reactivity after traumatic brain injury: implications for comorbid post-traumatic stress disorder.

Authors:  Ann N Hoffman; Anna N Taylor
Journal:  Behav Pharmacol       Date:  2019-04       Impact factor: 2.293

9.  Anticipatory prefrontal cortex activity underlies stress-induced changes in Pavlovian fear conditioning.

Authors:  Adam M Goodman; Nathaniel G Harnett; Muriah D Wheelock; Danielle R Hurst; Tyler R Orem; Ethan W Gossett; Chelsea A Dunaway; Sylvie Mrug; David C Knight
Journal:  Neuroimage       Date:  2018-03-16       Impact factor: 6.556

10.  Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories.

Authors:  Johannes Gräff; Nadine F Joseph; Meryl E Horn; Alireza Samiei; Jia Meng; Jinsoo Seo; Damien Rei; Adam W Bero; Trongha X Phan; Florence Wagner; Edward Holson; Jinbin Xu; Jianjun Sun; Rachael L Neve; Robert H Mach; Stephen J Haggarty; Li-Huei Tsai
Journal:  Cell       Date:  2014-01-16       Impact factor: 41.582

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