Literature DB >> 19710244

Recent progress in luteinizing hormone/human chorionic gonadotrophin hormone research.

Nafis A Rahman1, C V Rao.   

Abstract

The role of luteinizing hormone (LH) and human chorionic gonadotrophin hormone (hCG) in the regulation of normal reproductive functions in males and females is quite well established. Besides the use of hCG in the development of diagnostic immunoassays, it has been successfully used in the induction of final follicular maturation and ovulation in the assisted reproductive technologies. The basic and clinical research on the nongonadal actions of LH/hCG in the recent years has extended the potential of using these hormones in several clinical indications. Hereby we will analyze the advances in the LH/hCG research (briefly emphasizing the nongonadal research), which has the potential for multiple novel therapies in reproductive and the other areas of medicine.

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Year:  2009        PMID： 19710244     DOI： 10.1093/molehr/gap067

Source DB:  PubMed          Journal:  Mol Hum Reprod        ISSN： 1360-9947            Impact factor:   4.025


  9 in total

1.  Luteinizing hormone receptor deficiency increases the susceptibility to alkylating agent-induced lymphomagenesis in mice.

Authors:  Yinghao Yu; Fangping Yuan; Xian Li; Dexin Lin; Zijian Lan; C V Rao; Zhenmin Lei
Journal:  Horm Cancer       Date:  2010-10       Impact factor: 3.869

2.  Evidence for expression and functionality of FSH and LH/hCG receptors in human endometrium.

Authors:  Sandro Sacchi; Paola Sena; Chiara Degli Esposti; Jessica Lui; Antonio La Marca
Journal:  J Assist Reprod Genet       Date:  2018-07-04       Impact factor: 3.412

3.  Uphill battle: the saga of hCG research that led to a paradigm shift.

Authors:  C V Rao
Journal:  Indian J Med Res       Date:  2014-11       Impact factor: 2.375

4.  Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants.

Authors:  Anne E Chambers; Paul F Stanley; Harpal Randeva; Subhasis Banerjee
Journal:  Reprod Biol Endocrinol       Date:  2011-05-15       Impact factor: 5.211

5.  Circulating LH/hCG receptor (LHCGR) may identify pre-treatment IVF patients at risk of OHSS and poor implantation.

Authors:  Anne E Chambers; Krishnaveni P Nayini; Walter E Mills; Gillian M Lockwood; Subhasis Banerjee
Journal:  Reprod Biol Endocrinol       Date:  2011-12-23       Impact factor: 5.211

6.  Human chorionic gonadotropin and its relation to grade, stage and patient survival in ovarian cancer.

Authors:  Miriam Lenhard; Alexandra Tsvilina; Lan Schumacher; Markus Kupka; Nina Ditsch; Doris Mayr; Klaus Friese; Udo Jeschke
Journal:  BMC Cancer       Date:  2012-01-03       Impact factor: 4.430

7.  A Multicenter, Randomized, Equivalence Trial of a New Recombinant Human Chorionic Gonadotropin Preparation versus Ovitrelle® for Ovulation in Women Undergoing Intrauterine Insemination Following Ovarian Stimulation.

Authors:  Abha Majumdar; Rekha Sachan; Yogeshwar S Nandanwar; Rahul V Mayekar; Neelu Soni; Manish R Banker; Rajan S Vaidya; Manjeet Arora; Girish P Godbole; Gautam V Daftary; Ganesh H Divekar; James John
Journal:  J Hum Reprod Sci       Date:  2019 Jan-Mar

8.  Clinical Features of Craniopharyngioma With Tumoral Hemorrhage: A Retrospective Case-Controlled Study.

Authors:  Yusi Chen; Feng Hu; Junwen Wang; Kuan Huang; Weihua Liu; Yutang Tan; Kai Zhao; Qungen Xiao; Ting Lei; Kai Shu
Journal:  Front Surg       Date:  2022-03-14

9.  Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down's syndrome, preterm delivery and preeclampsia.

Authors:  Anne E Chambers; Christopher Griffin; Samantha A Naif; Ian Mills; Walter E Mills; Argyro Syngelaki; Kypros H Nicolaides; Subhasis Banerjee
Journal:  Reprod Biol Endocrinol       Date:  2012-12-17       Impact factor: 5.211
  9 in total

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