| Literature DB >> 19708706 |
Shibing Tang1, Jinmei He, Yongquan Sun, Liuer He, Xuegong She.
Abstract
A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of N-hydroxyl-4-toluenesulfonamide with alpha,beta-unsaturated aldehydes/ketones. This novel strategy is associated with readily available starting materials, mild conditions, high regioselectivity, and wide scope.Entities:
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Year: 2009 PMID： 19708706 DOI： 10.1021/ol901626n
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005