| Literature DB >> 19708640 |
Anna J Smith1, Lily K Abbott, Stephen F Martin.
Abstract
A general strategy for the conjugate addition of 2-heteroaryl nucleophiles to cyclic enones, unsaturated lactones, and unsaturated lactams in high enantioselectivities and yields is reported. The use of 2-heteroaryl titanates and zinc reagents offers a practical alternative to 2-heteroarylboronic acids, which are prone to undergo protodeboronation.Entities:
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Year: 2009 PMID： 19708640 DOI： 10.1021/ol9013975
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005