Literature DB >> 19708178

Prognostic factor on optimal debulking surgery by maximum effort for stage IIIC epithelial ovarian cancer.

Fumitoshi Terauchi1, Hirotaka Nishi, Tetsuya Moritake, Yukari Kobayashi, Takeo Nagashima, Takamoto Onodera, Atsuya Fujito, Daiei Nakayama, Keiichi Isaka.   

Abstract

OBJECTIVES: The aim of this study was to assess the prognostic factor of radical surgery in patients with stage IIIc ovarian cancer. STUDY
DESIGN: Fifty-two patients were subjected to the study. The complete resection or optimal primary cytoreductive surgery (OPCS) was set as the maximum effort, and the accomplishment rate and prognosis were assessed. In addition, the poor prognosis cases among the OPCS-accomplished were evaluated with several factors based on univariate and multivariate analyses.
RESULTS: The OPCS accomplishment rate was 84.6%. A worse prognosis was obtained in the more-than-4-weeks-delayed postoperative chemotherapy group, assessing poor-outcome cases in the OPCS group. A case that required more than three colon resections was the significant factor for the delay of postoperative chemotherapy.
CONCLUSIONS: OPCS should be performed with maximum effort to improve the prognosis of stage IIIc ovarian cancer. We should avoid any delay in starting postoperative chemotherapy. In cases that require more than three colon resections, it seems that 'perioperative management' should be reconsidered and that priority should be given to postoperative management so that chemotherapy can be started soon after the operation.

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Year:  2009        PMID: 19708178     DOI: 10.1111/j.1447-0756.2008.00928.x

Source DB:  PubMed          Journal:  J Obstet Gynaecol Res        ISSN: 1341-8076            Impact factor:   1.730


  3 in total

1.  Cyclin D1 predicts the prognosis of advanced serous ovarian cancer.

Authors:  Tomoko Hashimoto; Nozomu Yanaihara; Aikou Okamoto; Takashi Nikaido; Misato Saito; Satoshi Takakura; Makoto Yasuda; Hiroshi Sasaki; Kazunori Ochiai; Tadao Tanaka
Journal:  Exp Ther Med       Date:  2011-01-18       Impact factor: 2.447

2.  Clinical significance of systematic retroperitoneal lymphadenectomy during interval debulking surgery in advanced ovarian cancer patients.

Authors:  Haruko Iwase; Toshio Takada; Chiaki Iitsuka; Hidetaka Nomura; Akiko Abe; Tomoko Taniguchi; Ken Takizawa
Journal:  J Gynecol Oncol       Date:  2015-07-17       Impact factor: 4.401

3.  Survival and biomarker analysis for ovarian mucinous carcinoma according to invasive patterns: retrospective analysis and review literature.

Authors:  Taira Hada; Morikazu Miyamoto; Hiroki Ishibashi; Hiroko Matsuura; Takahiro Sakamoto; Soichiro Kakimoto; Hideki Iwahashi; Hitoshi Tsuda; Masashi Takano
Journal:  J Ovarian Res       Date:  2021-02-14       Impact factor: 4.234

  3 in total

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