Literature DB >> 19708094

Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma.

G Ugolini1, G Rosati, I Montroni, S Zanotti, A Manaresi, L Giampaolo, J Friederike Blume, M Taffurelli.   

Abstract

AIM: Analysing the effectiveness of a surgical procedure is mandatory in every modern health-care system. The aging of the population stresses the need for a good standard of care. This study tests the hypothesis that porthsmouth-physiologic operative severity score for enumeration of morbidity and mortality (P-POSSUM) and colorectal-POSSUM (CR-POSSUM) would be useful clinical auditing tools in colorectal cancer surgery for aged patients.
METHOD: One hundred and seventy-seven consecutive patients over 70 years of age underwent emergency or elective surgery from January 2003 to December 2005. Demographic, clinical and surgical information, score systems' prediction, complications and 30-day mortality data were prospectively entered in a comprehensive database. The observed over expected morbidity and mortality rate was calculated.
RESULTS: Thirty-day observed mortality was 10.3% (19/177) while P-POSSUM and CR-POSSUM expected mortality were, respectively, 11.21% (P = NS) and 13.08% (P = NS). Overall observed morbidity was 42.7%, P-POSSUM prediction was 59.3% (P = 0.002). Morbidity and mortality data were analysed for specific subgroups of patients (resection and anastomosis/resection and stoma/palliative; emergency/elective).
CONCLUSION: P-POSSUM and CR-POSSUM are useful tools to predict mortality in elderly patients. P-POSSUM significantly overestimated the risk of complications. A more accurate tool for preoperative assessment for aged patients is probably needed to predict the post-surgical outcome.

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Year:  2009        PMID: 19708094     DOI: 10.1111/j.1463-1318.2008.01676.x

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  8 in total

1.  Predicting post-operative mortality in patients undergoing colorectal surgery using P-POSSUM and CR-POSSUM scores: a prospective study.

Authors:  Edmund Leung; Ali M Ferjani; Nigel Stellard; Ling S Wong
Journal:  Int J Colorectal Dis       Date:  2009-07-30       Impact factor: 2.571

2.  Colorectal surgical mortality and morbidity in elderly patients: comparison of POSSUM, P-POSSUM, CR-POSSUM, and CR-BHOM.

Authors:  António Gomes; Ricardo Rocha; Rui Marinho; Marta Sousa; Nuno Pignatelli; Carla Carneiro; Vitor Nunes
Journal:  Int J Colorectal Dis       Date:  2014-11-28       Impact factor: 2.571

Review 3.  A systematic review of POSSUM and its related models as predictors of post-operative mortality and morbidity in patients undergoing surgery for colorectal cancer.

Authors:  Colin Hewitt Richards; Fiona E Leitch; Paul G Horgan; Donald C McMillan
Journal:  J Gastrointest Surg       Date:  2010-09-08       Impact factor: 3.452

4.  A collaborative transdisciplinary "geriatric surgery service" ensures consistent successful outcomes in elderly colorectal surgery patients.

Authors:  Kok-Yang Tan; Phyllis Tan; Lawrence Tan
Journal:  World J Surg       Date:  2011-07       Impact factor: 3.352

5.  Colorectal cancer treatment and follow-up in the elderly: an inexplicably different approach.

Authors:  Giovanni Li Destri; Mario Cavallaro; Maria Antonietta Trovato; Francesca Ferlito; Marine Castaing; Stefano Puleo
Journal:  Int Surg       Date:  2012 Jul-Sep

Review 6.  Personalized surgical management of colorectal cancer in elderly population.

Authors:  Giampaolo Ugolini; Federico Ghignone; Davide Zattoni; Giacomo Veronese; Isacco Montroni
Journal:  World J Gastroenterol       Date:  2014-04-14       Impact factor: 5.742

7.  Impact of age on outcome after colorectal cancer surgery in the elderly - a developing country perspective.

Authors:  Muhammad Rizwan Khan; Hassaan Bari; Syed Nabeel Zafar; Syed Ahsan Raza
Journal:  BMC Surg       Date:  2011-08-17       Impact factor: 2.102

8.  Comparison of long-term outcome between hemicolectomy and partial colectomy in the elderly: a large population-based study.

Authors:  Xu Guan; Hanqing Hu; Wei Chen; Zheng Jiang; Zheng Liu; Zhixun Zhao; Yinggang Chen; Guiyu Wang; Xishan Wang
Journal:  Oncotarget       Date:  2017-04-10
  8 in total

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