Literature DB >> 19707601

Risk factors and outcomes associated with chronic obstructive pulmonary disease exacerbations requiring hospitalization.

Katayoun Bahadori1, J Mark FitzGerald, Robert D Levy, Tharwat Fera, John Swiston.   

Abstract

BACKGROUND: Acute respiratory exacerbations are the most frequent cause of medical visits, hospitalization and death for chronic obstructive pulmonary disease (COPD) patients and, thus, exert a significant social and economic burden on society.
OBJECTIVE: To identify the risk factors associated with hospital readmission(s) for acute exacerbation(s) of COPD (AECOPD).
METHODS: A review of admission records from three large urban hospitals in Vancouver, British Columbia, identified 310 consecutive patients admitted for an AECOPD between April 1, 2001, and December 31, 2002. Logistic regression analysis was performed to identify risk factors for readmissions following an AECOPD.
RESULTS: During the study period, 38% of subjects were readmitted at least once. The mean (+/- SD) duration from the index admission to the first readmission was 5+/-4.08 months. Comparative analysis among the three hospitals identified a significant difference in readmission rates (54%, 36% and 18%, respectively). Logistic regression analysis revealed that preadmission home oxygen use (OR 2.55; 95%CI 1.45 to 4.42; P=0.001), history of a lung infection within the previous year (OR 1.73; 95% CI 1.01 to 2.97; P=0.048), other chronic respiratory disease (OR 1.78; 95% CI 1.06 to 2.99; P=0.03) and shorter length of hospital stay (OR 0.97; 95% CI 0.945 to 0.995; P=0.021) were independently associated with frequent readmissions for an AECOPD.
CONCLUSIONS: Hospital readmission rates for AECOPD were high. Only four clinical factors were found to be independently associated with COPD readmission. There was significant variability in the readmission rate among hospitals. This variability may be a result of differences in the patient populations that each hospital serves or may reflect variability in health care delivery at different institutions.

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Mesh:

Year:  2009        PMID: 19707601      PMCID: PMC2734440          DOI: 10.1155/2009/179263

Source DB:  PubMed          Journal:  Can Respir J        ISSN: 1198-2241            Impact factor:   2.409


  27 in total

1.  Risk factors for hospitalization for a chronic obstructive pulmonary disease exacerbation. EFRAM study.

Authors:  J Garcia-Aymerich; E Monsó; R M Marrades; J Escarrabill; M A Félez; J Sunyer; J M Antó
Journal:  Am J Respir Crit Care Med       Date:  2001-09-15       Impact factor: 21.405

2.  Muscle weakness is related to utilization of health care resources in COPD patients.

Authors:  M Decramer; R Gosselink; T Troosters; M Verschueren; G Evers
Journal:  Eur Respir J       Date:  1997-02       Impact factor: 16.671

3.  Quality of life and hospital re-admission in patients with chronic obstructive pulmonary disease.

Authors:  I M Osman; D J Godden; J A Friend; J S Legge; J G Douglas
Journal:  Thorax       Date:  1997-01       Impact factor: 9.139

4.  Hospital re-admission in patients with acute exacerbation of chronic obstructive pulmonary disease.

Authors:  A C Lau; L Y Yam; E Poon
Journal:  Respir Med       Date:  2001-11       Impact factor: 3.415

5.  Outcomes and health-related quality of life following hospitalization for an acute exacerbation of COPD.

Authors:  Qiuyue Wang; Jean Bourbeau
Journal:  Respirology       Date:  2005-06       Impact factor: 6.424

6.  Patients hospitalized for COPD have a high prevalence of modifiable risk factors for exacerbation (EFRAM study).

Authors:  J Garcia-Aymerich; E Barreiro; E Farrero; R M Marrades; J Morera; J M Antó
Journal:  Eur Respir J       Date:  2000-12       Impact factor: 16.671

7.  Predictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary disease.

Authors:  R Kessler; M Faller; G Fourgaut; B Mennecier; E Weitzenblum
Journal:  Am J Respir Crit Care Med       Date:  1999-01       Impact factor: 21.405

8.  Risk factors of readmission to hospital for a COPD exacerbation: a prospective study.

Authors:  J Garcia-Aymerich; E Farrero; M A Félez; J Izquierdo; R M Marrades; J M Antó
Journal:  Thorax       Date:  2003-02       Impact factor: 9.139

9.  Inhaled corticosteroids and hospitalisation due to exacerbation of COPD.

Authors:  J Bourbeau; P Ernst; D Cockcoft; S Suissa
Journal:  Eur Respir J       Date:  2003-08       Impact factor: 16.671

10.  Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD.

Authors:  Karin H Groenewegen; Annemie M W J Schols; Emiel F M Wouters
Journal:  Chest       Date:  2003-08       Impact factor: 9.410

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2.  Retrospective studies.

Authors:  Nick R Anthonisen
Journal:  Can Respir J       Date:  2009 Jul-Aug       Impact factor: 2.409

3.  Factors associated with the incidence of serious adverse events in patients admitted with COPD acute exacerbation.

Authors:  M-T García-Sanz; J-C Cánive-Gómez; N García-Couceiro; L Senín-Rial; S Alonso-Acuña; A Barreiro-García; E López-Val; L Valdés; F-J González-Barcala
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4.  Early hospital readmission is a predictor of one-year mortality in community-dwelling older Medicare beneficiaries.

Authors:  Hillary D Lum; Stephanie A Studenski; Howard B Degenholtz; Susan E Hardy
Journal:  J Gen Intern Med       Date:  2012-06-13       Impact factor: 5.128

Review 5.  The role of fluticasone propionate/salmeterol combination therapy in preventing exacerbations of COPD.

Authors:  Barbara P Yawn; Ibrahim Raphiou; Judith S Hurley; Anand A Dalal
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2010-06-03

6.  Prognostic Role of Chronic Obstructive Pulmonary Disease and Asthma Physiology Score for in-Hospital and 1-year Mortality in Patients with Acute Exacerbations of COPD.

Authors:  Zixiong Zeng; Qin Liu; Xiaoying Huang; Chunyan Lu; Juan Cheng; Yuqun Li; Guoping Hu; Liping Wei
Journal:  Can Respir J       Date:  2022-04-25       Impact factor: 2.130

7.  Outcomes associated with acute exacerbations of chronic obstructive pulmonary disorder requiring hospitalization.

Authors:  Gajanan S Gaude; B P Rajesh; Alisha Chaudhury; Jyothi Hattiholi
Journal:  Lung India       Date:  2015 Sep-Oct

8.  Home oxygen therapy reduces risk of hospitalisation in patients with chronic obstructive pulmonary disease: a population-based retrospective cohort study, 2005-2012.

Authors:  Kyoung Hee Cho; Young Sam Kim; Chung Mo Nam; Tae Hyun Kim; Sun Jung Kim; Kyu-Tae Han; Eun-Cheol Park
Journal:  BMJ Open       Date:  2015-11-30       Impact factor: 2.692

9.  COPD exacerbations admitted to intensive care unit. Organization, mortality, and noninvasive or invasive mechanical ventilation strategies: are they sufficiently well known?

Authors:  Antonio M Esquinas
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2013-07-29

10.  Development and validation of a model to predict the risk of exacerbations in chronic obstructive pulmonary disease.

Authors:  Loes C M Bertens; Johannes B Reitsma; Karel G M Moons; Yvonne van Mourik; Jan Willem J Lammers; Berna D L Broekhuizen; Arno W Hoes; Frans H Rutten
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2013-10-10
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