| Literature DB >> 19706274 |
David del Alamo1, François Schweisguth.
Abstract
Lateral inhibition, by which single cells become distinct from their neighbours, can be mediated by Notch signalling during animal development. Signalling directionality is presumably achieved by downregulation of the Notch ligand in signal-receiving cells. New evidence suggests that cis-inhibition of the receptor in the ligand-sending cell might also provide directionality.Mesh：
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Year: 2009 PMID： 19706274 DOI： 10.1016/j.cub.2009.07.025
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834