BACKGROUND: Weight loss and nutritional status 5 or more years after Roux-en-Y gastric bypass was prospectively documented. The hypothesis was that even after clinical adaptation, imbalances might still occur. METHODS: Seventy-five consecutive patients (age 49.3 +/- 10.6 years, 89.3% females) were recruited 83.4 +/- 14.3 months after the intervention. Weight loss and nutritional abnormalities were registered. RESULTS: Body mass index (BMI) was 56.5 +/- 10.0 preoperatively, 29.4 +/- 6. 2 by 24 months and 34.4 +/- 14.6 when last seen. Major current deficit occurred for magnesium (32.1% of the patients), hemoglobin (50.8%), iron (29.8%), ferritin (36.0%), zinc (40.5%), vitamin B(12) (61.8%), vitamin D(3) (60.5%), and beta-carotene (56.8%). Low preoperative measurements had already been unveiled for iron, transferrin, zinc, and vitamin B(12). Total drug consumption tended to decrease after operation, and present findings correlated with excess weight loss (EWL). Also presence of diabetes and BMI value were predictors of long-term EWL, along with biochemical profile by 2 years. Multivitamin supplementation and gastrointestinal complaints partially correlated with nutritional results. CONCLUSIONS: (1) Good initial weight loss with moderate late regain, anemia, and multiple nutrient deficits was the common pattern. (2) Massive weight loss, frequent vomiting, dumping syndrome, and women in reproductive age were risk factors for hemoglobin or vitamin deficits, whereas superobesity, diabetes, and use of multiple drugs were associated with EWL result. (3) Most laboratory tests became stable by 2 years and along with BMI correlated with late EWL. (4) Two-year nutritional investigation is especially recommended because of its long-term predictive value.
BACKGROUND:Weight loss and nutritional status 5 or more years after Roux-en-Y gastric bypass was prospectively documented. The hypothesis was that even after clinical adaptation, imbalances might still occur. METHODS: Seventy-five consecutive patients (age 49.3 +/- 10.6 years, 89.3% females) were recruited 83.4 +/- 14.3 months after the intervention. Weight loss and nutritional abnormalities were registered. RESULTS: Body mass index (BMI) was 56.5 +/- 10.0 preoperatively, 29.4 +/- 6. 2 by 24 months and 34.4 +/- 14.6 when last seen. Major current deficit occurred for magnesium (32.1% of the patients), hemoglobin (50.8%), iron (29.8%), ferritin (36.0%), zinc (40.5%), vitamin B(12) (61.8%), vitamin D(3) (60.5%), and beta-carotene (56.8%). Low preoperative measurements had already been unveiled for iron, transferrin, zinc, and vitamin B(12). Total drug consumption tended to decrease after operation, and present findings correlated with excess weight loss (EWL). Also presence of diabetes and BMI value were predictors of long-term EWL, along with biochemical profile by 2 years. Multivitamin supplementation and gastrointestinal complaints partially correlated with nutritional results. CONCLUSIONS: (1) Good initial weight loss with moderate late regain, anemia, and multiple nutrient deficits was the common pattern. (2) Massive weight loss, frequent vomiting, dumping syndrome, and women in reproductive age were risk factors for hemoglobin or vitamin deficits, whereas superobesity, diabetes, and use of multiple drugs were associated with EWL result. (3) Most laboratory tests became stable by 2 years and along with BMI correlated with late EWL. (4) Two-year nutritional investigation is especially recommended because of its long-term predictive value.
Authors: Robson K Ishida; Joel Faintuch; Ana M R Paula; Christiane A Risttori; Sabrina N Silva; Elaine S Gomes; Rejane Mattar; Rogerio Kuga; Adriana S Ribeiro; Paulo Sakai; Hermes V Barbeiro; Denise F Barbeiro; Francisco G Soriano; Ivan Cecconello Journal: Obes Surg Date: 2007-06 Impact factor: 4.129
Authors: Nicolas V Christou; John S Sampalis; Moishe Liberman; Didier Look; Stephane Auger; Alexander P H McLean; Lloyd D MacLean Journal: Ann Surg Date: 2004-09 Impact factor: 12.969
Authors: R E Brolin; J H Gorman; R C Gorman; A J Petschenik; L J Bradley; H A Kenler; R P Cody Journal: J Gastrointest Surg Date: 1998 Sep-Oct Impact factor: 3.452
Authors: Joel Faintuch; Mitsunori Matsuda; Maria Emilia L F Cruz; Marlene M Silva; Marcelo P Teivelis; Arthur B Garrido; J J Gama-Rodrigues Journal: Obes Surg Date: 2004-02 Impact factor: 4.129
Authors: Renee A Mischler; Seth M Armah; Bruce A Craig; Arthur D Rosen; Ambar Banerjee; Don J Selzer; Jennifer N Choi; Nana Gletsu-Miller Journal: Obes Surg Date: 2018-02 Impact factor: 4.129
Authors: Adriana V Safatle-Ribeiro; Pedro A Petersen; Dilson S Pereira Filho; Carlos E P Corbett; Joel Faintuch; Robson Ishida; Paulo Sakai; Ivan Cecconello; Ulysses Ribeiro Journal: Obes Surg Date: 2013-10 Impact factor: 4.129
Authors: Kamal K Mahawar; Alastair Reid; Yitka Graham; Lindes Callejas-Diaz; Chetan Parmar; William Rj Carr; Neil Jennings; Rishi Singhal; Peter K Small Journal: Obes Surg Date: 2018-07 Impact factor: 4.129
Authors: Carlijn Kuin; Floor den Ouden; Hans Brandts; Laura Deden; Eric Hazebroek; Marcel van Borren; Hans de Boer Journal: Obes Surg Date: 2019-10 Impact factor: 4.129
Authors: Ben Gys; Philip Plaeke; Bas Lamme; Thierry Lafullarde; Niels Komen; Anthony Beunis; Guy Hubens Journal: Obes Surg Date: 2019-06 Impact factor: 4.129
Authors: Jens Homan; Wendy Schijns; Edo O Aarts; Ignace M C Janssen; Frits J Berends; Hans de Boer Journal: Obes Surg Date: 2018-01 Impact factor: 4.129
Authors: Angela Gadelha Ribeiro; Maria José de Carvalho Costa; Joel Faintuch; Maria Carolina Gonçalves Dias Journal: Clinics (Sao Paulo) Date: 2009 Impact factor: 2.365