Literature DB >> 19705082

ATF3 transcription factor and its emerging roles in immunity and cancer.

Matthew R Thompson1, Dakang Xu, Bryan R G Williams.   

Abstract

Activating transcription factor 3 (ATF3) is a member of the ATF/cyclic AMP response element-binding (ATF/CREB) family of transcription factors. It is an adaptive-response gene that participates in cellular processes to adapt to extra- and/or intracellular changes, where it transduces signals from various receptors to activate or repress gene expression. Advances made in understanding the immunobiology of Toll-like receptors have recently generated new momentum for the study of ATF3 in immunity. Moreover, the role of ATF3 in the regulation of the cell cycle and apoptosis has important implications for understanding susceptibility to and progression of several cancers.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19705082      PMCID： PMC2783469          DOI： 10.1007/s00109-009-0520-x

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  50 in total

Review 1.  ATF3 and stress responses.

Authors:  T Hai; C D Wolfgang; D K Marsee; A E Allen; U Sivaprasad
Journal:  Gene Expr       Date:  1999

2.  gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

Authors:  C D Wolfgang; B P Chen; J L Martindale; N J Holbrook; T Hai
Journal:  Mol Cell Biol       Date:  1997-11       Impact factor: 4.272

3.  Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.

Authors:  Chunhong Yan; Md S Jamaluddin; Bharat Aggarwal; Jeffrey Myers; Douglas D Boyd
Journal:  Mol Cancer Ther       Date:  2005-02       Impact factor: 6.261

4.  Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response.

Authors:  T W Fawcett; J L Martindale; K Z Guyton; T Hai; N J Holbrook
Journal:  Biochem J       Date:  1999-04-01       Impact factor: 3.857

5.  Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling.

Authors:  Viqar Syed; Kasturi Mukherjee; James Lyons-Weiler; Kin-Mang Lau; Tetsuo Mashima; Takashi Tsuruo; Shuk-mei Ho
Journal:  Oncogene       Date:  2005-03-03       Impact factor: 9.867

6.  Introduction of gadd153 gene into gastric cancer cells can modulate sensitivity to anticancer agents in association with apoptosis.

Authors:  R Kim; Y Ohi; H Inoue; K Aogi; T Toge
Journal:  Anticancer Res       Date:  1999 May-Jun       Impact factor: 2.480

7.  The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).

Authors:  Frank G Bottone; Yuseok Moon; Jong Sik Kim; Brenda Alston-Mills; Minako Ishibashi; Thomas E Eling
Journal:  Mol Cancer Ther       Date:  2005-05       Impact factor: 6.261

8.  CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum.

Authors:  H Zinszner; M Kuroda; X Wang; N Batchvarova; R T Lightfoot; H Remotti; J L Stevens; D Ron
Journal:  Genes Dev       Date:  1998-04-01       Impact factor: 11.361

9.  Curcumin-induced GADD153 gene up-regulation in human colon cancer cells.

Authors:  David W Scott; George Loo
Journal:  Carcinogenesis       Date:  2004-07-22       Impact factor: 4.944

10.  Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals.

Authors:  Vladimir Litvak; Stephen A Ramsey; Alistair G Rust; Daniel E Zak; Kathleen A Kennedy; Aaron E Lampano; Matti Nykter; Ilya Shmulevich; Alan Aderem
Journal:  Nat Immunol       Date:  2009-03-08       Impact factor: 25.606
View more
  130 in total

Review 1.  The transcription factor network associated with the amino acid response in mammalian cells.

Authors:  Michael S Kilberg; Mukundh Balasubramanian; Lingchen Fu; Jixiu Shan
Journal:  Adv Nutr       Date:  2012-05-01       Impact factor: 8.701

2.  Global DNA methylation remodeling accompanies CD8 T cell effector function.

Authors:  Christopher D Scharer; Benjamin G Barwick; Benjamin A Youngblood; Rafi Ahmed; Jeremy M Boss
Journal:  J Immunol       Date:  2013-08-16       Impact factor: 5.422

3.  ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types.

Authors:  Anderly C Chüeh; Janson W T Tse; Michael Dickinson; Paul Ioannidis; Laura Jenkins; Lars Togel; BeeShin Tan; Ian Luk; Mercedes Davalos-Salas; Rebecca Nightingale; Matthew R Thompson; Bryan R G Williams; Guillaume Lessene; Erinna F Lee; Walter D Fairlie; Amardeep S Dhillon; John M Mariadason
Journal:  Clin Cancer Res       Date:  2017-06-13       Impact factor: 12.531

4.  Prostaglandin E2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.

Authors:  Kotha Subbaramaiah; Neil M Iyengar; Monica Morrow; Olivier Elemento; Xi Kathy Zhou; Andrew J Dannenberg
Journal:  J Biol Chem       Date:  2018-11-08       Impact factor: 5.157

5.  Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.

Authors:  Kyungsil Yoon; Syng-Ook Lee; Sung-Dae Cho; Kyounghyun Kim; Shaheen Khan; Stephen Safe
Journal:  Carcinogenesis       Date:  2011-03-01       Impact factor: 4.944

6.  Novel link of anti-apoptotic ATF3 with pro-apoptotic CTMP in the ischemic brain.

Authors:  Chien-Yu Huang; Jin-Jer Chen; Jui-Sheng Wu; Hsin-Da Tsai; Heng Lin; Yu-Ting Yan; Chung Y Hsu; Yuan-Soon Ho; Teng-Nan Lin
Journal:  Mol Neurobiol       Date:  2014-04-26       Impact factor: 5.590

7.  Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis.

Authors:  Rafael Kramann; Flavia Machado; Haojia Wu; Tetsuro Kusaba; Konrad Hoeft; Rebekka K Schneider; Benjamin D Humphreys
Journal:  JCI Insight       Date:  2018-05-03

Review 8.  Regulatory SNPs and transcriptional factor binding sites in ADRBK1, AKT3, ATF3, DIO2, TBXA2R and VEGFA.

Authors:  Norman E Buroker
Journal:  Transcription       Date:  2014-10-31

9.  IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus-infected human macrophages.

Authors:  Tshifhiwa Magoro; Aditya Dandekar; Lucas T Jennelle; Rohan Bajaj; Gabriel Lipkowitz; Angelina R Angelucci; Pascal O Bessong; Young S Hahn
Journal:  J Biol Chem       Date:  2019-08-02       Impact factor: 5.157

10.  Glucocorticoid Induces Hepatic Steatosis by Inhibiting Activating Transcription Factor 3 (ATF3)/S100A9 Protein Signaling in Granulocytic Myeloid-derived Suppressor Cells.

Authors:  Yu-Feng Liu; Jian-Yang Wei; Mao-Hua Shi; Hua Jiang; Jie Zhou
Journal:  J Biol Chem       Date:  2016-08-29       Impact factor: 5.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.