Literature DB >> 19704851

Cytosolic cysteine in redox signaling.

M Carmen López-Martín1, Luis C Romero, Cecilia Gotor.   

Abstract

CYSTEINE BIOSYNTHESIS IN PLANTS TAKES PLACE IN THE THREE CELLULAR COMPARTMENTS WITH AUTONOMOUS PROTEIN BIOSYNTHESIS MACHINERY: cytosol, plastids and mitochondria. This sulfur-containing molecule is synthesized sequentially in these compartments by two enzymatic families, the serine acetyltransferases and the O-acetylserine(thiol) lyases. Each family consists of several isoforms that differ in subcellular localization and abundance. Why so many isoforms are required in plant cell for cysteine biosynthesis has remained unknown to date. The characterization of gene-specific knockout mutants has started to address this question. In our recent work, we have performed a detailed analysis of the Arabidopsis oas-a1 null mutant and showed that the antioxidant capacity of the cytosol is compromised, highlighting the contribution of cytosolic Cys in redox signaling.

Entities:  

Keywords:  Arabidopsis; O-acetylserine(thiol)lyase; cysteine biosynthesis; redox regulation

Year:  2008        PMID： 19704851      PMCID： PMC2637515          DOI： 10.4161/psb.3.10.6289

Source DB:  PubMed          Journal:  Plant Signal Behav        ISSN： 1559-2316


  8 in total

1.  O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana.

Authors:  Markus Wirtz; Michel Droux; Rüdiger Hell
Journal:  J Exp Bot       Date:  2004-07-16       Impact factor: 6.992

2.  Interactions between serine acetyltransferase and O-acetylserine (thiol) lyase in higher plants--structural and kinetic properties of the free and bound enzymes.

Authors:  M Droux; M L Ruffet; R Douce; D Job
Journal:  Eur J Biochem       Date:  1998-07-01

Review 3.  Glutathione homeostasis and redox-regulation by sulfhydryl groups.

Authors:  Andreas J Meyer; Rüdiger Hell
Journal:  Photosynth Res       Date:  2005-11-11       Impact factor: 3.573

4.  Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling.

Authors:  Yvonne S Nkabyo; Young-Mi Go; Thomas R Ziegler; Dean P Jones
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2005-03-03       Impact factor: 4.052

5.  Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms.

Authors:  Sigrun Reumann; Lavanya Babujee; Changle Ma; Stephanie Wienkoop; Tanja Siemsen; Gerardo E Antonicelli; Nicolas Rasche; Franziska Lüder; Wolfram Weckwerth; Olaf Jahn
Journal:  Plant Cell       Date:  2007-10-19       Impact factor: 11.277

6.  Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis.

Authors:  Corinna Heeg; Cordula Kruse; Ricarda Jost; Michael Gutensohn; Thomas Ruppert; Markus Wirtz; Rüdiger Hell
Journal:  Plant Cell       Date:  2008-01-25       Impact factor: 11.277

7.  Evidence for a direct link between glutathione biosynthesis and stress defense gene expression in Arabidopsis.

Authors:  Louise Ball; Gian-Paolo Accotto; Ulrike Bechtold; Gary Creissen; Dietmar Funck; Ana Jimenez; Baldeep Kular; Nicola Leyland; Jaime Mejia-Carranza; Helen Reynolds; Stanislaw Karpinski; Philip M Mullineaux
Journal:  Plant Cell       Date:  2004-08-12       Impact factor: 11.277

8.  The serine acetyltransferase gene family in Arabidopsis thaliana and the regulation of its expression by cadmium.

Authors:  Jonathan R Howarth; José R Domínguez-Solís; Gloria Gutiérrez-Alcalá; John L Wray; Luis C Romero; Cecilia Gotor
Journal:  Plant Mol Biol       Date:  2003-03       Impact factor: 4.076
  8 in total
  6 in total

1.  Cysteine-generated sulfide in the cytosol negatively regulates autophagy and modulates the transcriptional profile in Arabidopsis.

Authors:  Consolación Álvarez; Irene García; Inmaculada Moreno; María Esther Pérez-Pérez; José L Crespo; Luis C Romero; Cecilia Gotor
Journal:  Plant Cell       Date:  2012-11-09       Impact factor: 11.277

2.  Purification and characterization of ZmRIP1, a novel reductant-inhibited protein tyrosine phosphatase from maize.

Authors:  Bingbing Li; Yanxia Zhao; Liyan Liang; Huibo Ren; Yu Xing; Lin Chen; Mingzhu Sun; Yuanhua Wang; Yu Han; Haifeng Jia; Conglin Huang; Zhongyi Wu; Wensuo Jia
Journal:  Plant Physiol       Date:  2012-04-23       Impact factor: 8.340

3.  An O-acetylserine(thiol)lyase homolog with L-cysteine desulfhydrase activity regulates cysteine homeostasis in Arabidopsis.

Authors:  Consolación Alvarez; Leticia Calo; Luis C Romero; Irene García; Cecilia Gotor
Journal:  Plant Physiol       Date:  2009-12-02       Impact factor: 8.340

Review 4.  ATP-sulfurylase, sulfur-compounds, and plant stress tolerance.

Authors:  Naser A Anjum; Ritu Gill; Manjeri Kaushik; Mirza Hasanuzzaman; Eduarda Pereira; Iqbal Ahmad; Narendra Tuteja; Sarvajeet S Gill
Journal:  Front Plant Sci       Date:  2015-04-07       Impact factor: 5.753

Review 5.  β-N-Oxalyl-l-α,β-diaminopropionic Acid (β-ODAP) Content in Lathyrus sativus: The Integration of Nitrogen and Sulfur Metabolism through β-Cyanoalanine Synthase.

Authors:  Quanle Xu; Fengjuan Liu; Peng Chen; Joseph M Jez; Hari B Krishnan
Journal:  Int J Mol Sci       Date:  2017-02-28       Impact factor: 5.923

6.  Code-assisted discovery of TAL effector targets in bacterial leaf streak of rice reveals contrast with bacterial blight and a novel susceptibility gene.

Authors:  Raul A Cernadas; Erin L Doyle; David O Niño-Liu; Katherine E Wilkins; Timothy Bancroft; Li Wang; Clarice L Schmidt; Rico Caldo; Bing Yang; Frank F White; Dan Nettleton; Roger P Wise; Adam J Bogdanove
Journal:  PLoS Pathog       Date:  2014-02-27       Impact factor: 6.823
  6 in total

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