OBJECTIVES: To investigate whether dietary glycaemic index (GI) and glycaemic load (GL) were associated with subsequent weight and waist circumference change. DESIGN: Population-based prospective cohort study. SETTING: Five European countries, which are Denmark, Germany, Italy, The Netherlands and the United Kingdom. PARTICIPANTS: A total of 89,432 participants, aged 20-78 years (mean =53 years) at baseline and followed for 1.9-12.5 years (mean=6.5 years). All participants were free of self-reported cancer, cardiovascular diseases and diabetes at baseline. METHODS: Glycaemic index and GL were calculated on the basis of dietary intake assessed by food frequency questionnaires and by using a GI table developed for this study with published GI values as the main sources. Anthropometric data were collected both at baseline and at the end of follow-up. Multiple linear regression analyses were conducted in each centre and random-effect meta-analyses were used to combine the effects. Adjustment was made for baseline anthropometrics, demographic and lifestyle factors, follow-up duration and other dietary factors. RESULTS: Mean GI and GL were 57 and 134, respectively. Associations of GI and GL with subsequent changes of weight and waist circumference were heterogeneous across centres. Overall, with every 10-unit higher in GI, weight increased by 34 g per year (95% confidence interval (CI): -47, 115) and waist circumference increased by 0.19 cm per year (95% CI: 0.11, 0.27). With every 50-unit higher in GL, weight increased by 10 g per year (95% CI: -65, 85) and waist circumference increased by 0.06 cm per year (95% CI: -0.01, 0.13). CONCLUSIONS: Our findings do not support an effect of GI or GL on weight change. The positively significant association between GI, not GL, and subsequent gain in waist circumference may imply a beneficial role of lower GI diets in the prevention of abdominal obesity. However, further studies are needed to confirm this finding given the small effect observed in this study.
OBJECTIVES: To investigate whether dietary glycaemic index (GI) and glycaemic load (GL) were associated with subsequent weight and waist circumference change. DESIGN: Population-based prospective cohort study. SETTING: Five European countries, which are Denmark, Germany, Italy, The Netherlands and the United Kingdom. PARTICIPANTS: A total of 89,432 participants, aged 20-78 years (mean =53 years) at baseline and followed for 1.9-12.5 years (mean=6.5 years). All participants were free of self-reported cancer, cardiovascular diseases and diabetes at baseline. METHODS: Glycaemic index and GL were calculated on the basis of dietary intake assessed by food frequency questionnaires and by using a GI table developed for this study with published GI values as the main sources. Anthropometric data were collected both at baseline and at the end of follow-up. Multiple linear regression analyses were conducted in each centre and random-effect meta-analyses were used to combine the effects. Adjustment was made for baseline anthropometrics, demographic and lifestyle factors, follow-up duration and other dietary factors. RESULTS: Mean GI and GL were 57 and 134, respectively. Associations of GI and GL with subsequent changes of weight and waist circumference were heterogeneous across centres. Overall, with every 10-unit higher in GI, weight increased by 34 g per year (95% confidence interval (CI): -47, 115) and waist circumference increased by 0.19 cm per year (95% CI: 0.11, 0.27). With every 50-unit higher in GL, weight increased by 10 g per year (95% CI: -65, 85) and waist circumference increased by 0.06 cm per year (95% CI: -0.01, 0.13). CONCLUSIONS: Our findings do not support an effect of GI or GL on weight change. The positively significant association between GI, not GL, and subsequent gain in waist circumference may imply a beneficial role of lower GI diets in the prevention of abdominal obesity. However, further studies are needed to confirm this finding given the small effect observed in this study.
Authors: K Murakami; T A McCaffrey; A M Gallagher; C E Neville; C A Boreham; M B E Livingstone Journal: Int J Obes (Lond) Date: 2013-05-03 Impact factor: 5.095
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Authors: Sofus C Larsen; Lars Ängquist; Jane N Østergaard; Tarunveer S Ahluwalia; Karani S Vimaleswaran; Nina Roswall; Lotte M Mortensen; Birgit M Nielsen; Anne Tjønneland; Nicholas J Wareham; Domenico Palli; Giovanna Masala; Wim H M Saris; Daphne L van der A; Jolanda M A Boer; Edith J M Feskens; Heiner Boeing; Marianne U Jakobsen; Ruth J F Loos; Thorkild I A Sørensen; Kim Overvad Journal: J Nutr Date: 2016-02-10 Impact factor: 4.798
Authors: Dora Romaguera; Lars Angquist; Huaidong Du; Marianne Uhre Jakobsen; Nita G Forouhi; Jytte Halkjaer; Edith J M Feskens; Daphne L van der A; Giovanna Masala; Annika Steffen; Domenico Palli; Nicholas J Wareham; Kim Overvad; Anne Tjønneland; Heiner Boeing; Elio Riboli; Thorkild I A Sørensen Journal: PLoS One Date: 2010-07-14 Impact factor: 3.240
Authors: Huaidong Du; Karani S Vimaleswaran; Lars Angquist; Rikke D Hansen; Daphne L van der A; Claus Holst; Anne Tjønneland; Kim Overvad; Marianne Uhre Jakobsen; Heiner Boeing; Karina Meidtner; Domenico Palli; Giovanna Masala; Nabila Bouatia-Naji; Wim H M Saris; Edith J M Feskens; Nicolas J Wareham; Thorkild I A Sørensen; Ruth J F Loos Journal: PLoS One Date: 2011-02-24 Impact factor: 3.240
Authors: Henri Hooton; Lars Angquist; Claus Holst; Jorg Hager; Francis Rousseau; Rikke D Hansen; Anne Tjønneland; Nina Roswall; Daphne L van der A; Kim Overvad; Marianne Uhre Jakobsen; Heiner Boeing; Karina Meidtner; Domenico Palli; Giovanna Masala; Nabila Bouatia-Naji; Wim H M Saris; Edith J M Feskens; Nicolas J Wareham; Karani S Vimaleswaran; Dominique Langin; Ruth J F Loos; Thorkild I A Sørensen; Karine Clément Journal: PLoS One Date: 2012-07-23 Impact factor: 3.240