John D Berne1, Scott H Norwood. 1. Division of Trauma Surgery, East Texas Medical Center, Tyler, Texas 75701, USA. jberne@aol.com
Abstract
INTRODUCTION: Blunt injuries to the vertebral artery (BVI) are rare. Recent improvements in the multidetector computer tomography (MDCT) technology and increased use of screening protocols have led to a greater number of these injuries identified. Well-defined treatment recommendations are still lacking, and it is unclear whether screening and treatment lead to improved outcome. METHODS: All patients who met predefined screening criteria were screened for BVI with a MDCT angiogram (MDCT-A). All patients identified with BVI were treated based on injury grade and associated injuries. Hospital course, morbidity, mortality, and follow-up were recorded and analyzed. RESULTS: A total of 8,292 patients were admitted for blunt injuries during this time period. Forty-four patients were found to have 47 BVI (three bilateral). Pharmacologic treatment with anticoagulants (AC)-heparin and warfarin-or an antiplatelet agent-clopidogrel and aspirin-was initiated in 37 patients (84%). Angiographic coiling was performed in eight patients (18%), and two (5%) had endovascular stents placed. Four patients developed signs of cerebral ischemia (9%), of whom three died and one recovered completely. Overall mortality rate was 16% (7/44). BVI-related mortality occurred in three patients (7%). Of these, two patients had bilateral vertebral artery occlusion or transaction, and death was considered nonpreventable. One death occurred in a patient with a unilateral vertebral dissection developed a posterior circulation infarct. Anticoagulation was felt to be contraindicated in this patient initially due to intracranial hemorrhage. This was deemed the only potentially preventable BVI-related mortality. Annual BVI-related mortality rate in the 4 years before initiating the screening protocol was 0.75 cases per year. During this study period, it was 0.57 cases per year. CONCLUSION: Under an aggressive screening and individualized treatment protocol for BVI, we had very few potentially preventable BVI-related strokes and deaths. We are unable to conclude; however, based on historical controls that either screening or treatment improved overall outcome.
INTRODUCTION: Blunt injuries to the vertebral artery (BVI) are rare. Recent improvements in the multidetector computer tomography (MDCT) technology and increased use of screening protocols have led to a greater number of these injuries identified. Well-defined treatment recommendations are still lacking, and it is unclear whether screening and treatment lead to improved outcome. METHODS: All patients who met predefined screening criteria were screened for BVI with a MDCT angiogram (MDCT-A). All patients identified with BVI were treated based on injury grade and associated injuries. Hospital course, morbidity, mortality, and follow-up were recorded and analyzed. RESULTS: A total of 8,292 patients were admitted for blunt injuries during this time period. Forty-four patients were found to have 47 BVI (three bilateral). Pharmacologic treatment with anticoagulants (AC)-heparin and warfarin-or an antiplatelet agent-clopidogrel and aspirin-was initiated in 37 patients (84%). Angiographic coiling was performed in eight patients (18%), and two (5%) had endovascular stents placed. Four patients developed signs of cerebral ischemia (9%), of whom three died and one recovered completely. Overall mortality rate was 16% (7/44). BVI-related mortality occurred in three patients (7%). Of these, two patients had bilateral vertebral artery occlusion or transaction, and death was considered nonpreventable. One death occurred in a patient with a unilateral vertebral dissection developed a posterior circulation infarct. Anticoagulation was felt to be contraindicated in this patient initially due to intracranial hemorrhage. This was deemed the only potentially preventable BVI-related mortality. Annual BVI-related mortality rate in the 4 years before initiating the screening protocol was 0.75 cases per year. During this study period, it was 0.57 cases per year. CONCLUSION: Under an aggressive screening and individualized treatment protocol for BVI, we had very few potentially preventable BVI-related strokes and deaths. We are unable to conclude; however, based on historical controls that either screening or treatment improved overall outcome.
Authors: Vijay M Ravindra; Robert J Bollo; Walavan Sivakumar; Hassan Akbari; Robert P Naftel; David D Limbrick; Andrew Jea; Stephen Gannon; Chevis Shannon; Yekaterina Birkas; George L Yang; Colin T Prather; John R Kestle; Jay Riva-Cambrin Journal: J Neurotrauma Date: 2016-07-25 Impact factor: 5.269