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Literature DB >> 19703390

Breast cancer stem cells: eradication by differentiation therapy?

Abstract

During metastasis, migrating breast cancer stem cells undergo a loss of polarity leading to an epithelial-to-mesenchymal transition (EMT). Gupta et al. (2009) use this attribute of cancer stem cells to develop a high-throughput screen, which successfully identifies small molecules that specifically inhibit cancer stem cell proliferation through the induction of differentiation.

Entities: Disease

Mesh：

Year: 2009 PMID： 19703390 DOI： 10.1016/j.cell.2009.08.007

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

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Cited

19 in total

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Journal: J Clin Invest Date: 2012-07-09 Impact factor: 14.808

Review 2. Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming.

Authors: Custodia García-Jiménez; Colin R Goding
Journal: Cell Metab Date: 2018-12-20 Impact factor: 27.287

3. hMSC-mediated concurrent delivery of endostatin and carboxylesterase to mouse xenografts suppresses glioma initiation and recurrence.

Authors: Jinlong Yin; Jun-Kyum Kim; Jai-Hee Moon; Samuel Beck; Dachuan Piao; Xun Jin; Sung-Hak Kim; Young Chang Lim; Do-Hyun Nam; Seungkwon You; Hyunggee Kim; Yun-Jaie Choi
Journal: Mol Ther Date: 2011-03-08 Impact factor: 11.454

4. A retroperitoneal NF1-independent malignant peripheral nerve sheath tumor with elevated serum CA125: case report and discussion.

Authors: Bing Yan; Xianze Meng; Bian Shi; Jun Shi; Zhifeng Qin; Pinkang Wei
Journal: J Neurooncol Date: 2012-04-19 Impact factor: 4.130

Breast cancer stem cells: eradication by differentiation therapy?

1. Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17.

Review 2. Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming.

3. hMSC-mediated concurrent delivery of endostatin and carboxylesterase to mouse xenografts suppresses glioma initiation and recurrence.

4. A retroperitoneal NF1-independent malignant peripheral nerve sheath tumor with elevated serum CA125: case report and discussion.

Review 5. Interpretation of interlocking key issues of cancer stem cells in malignant solid tumors.

Review 6. Cancer stem cells: the 'heartbeat' of gastric cancer.

7. Annexin A1 attenuates EMT and metastatic potential in breast cancer.

8. Salinomycin induces calpain and cytochrome c-mediated neuronal cell death.

9. Sequential expression of putative stem cell markers in gastric carcinogenesis.

10. Cancer stem cells and side population cells in breast cancer and metastasis.