Literature DB >> 1970233

New antitumor promoters: (-)-epigallocatechin gallate and sarcophytols A and B.

H Fujiki1, M Suganuma, H Suguri, K Takagi, S Yoshizawa, A Ootsuyama, H Tanooka, T Okuda, M Kobayashi, T Sugimura.   

Abstract

EGCG, the main constituent of green tea, and sarcophytols A and B, isolated from a soft coral, inhibited tumor promotion by teleocidin in a two-stage carcinogenesis experiment on mouse skin. EGCG and sarcophytols showed inhibition of tumor development by chemical carcinogenesis. A possibility of developing these compounds as cancer chemopreventives for human beings is discussed.

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Year:  1990        PMID: 1970233     DOI: 10.1007/978-1-4615-9561-8_17

Source DB:  PubMed          Journal:  Basic Life Sci        ISSN: 0090-5542


  2 in total

1.  Monoamine metabolites, iron induced seizures, and the anticonvulsant effect of tannins.

Authors:  H Kabuto; I Yokoi; A Mori
Journal:  Neurochem Res       Date:  1992-06       Impact factor: 3.996

2.  Inhibitory effect of sarcophytol A on development of spontaneous hepatomas in mice.

Authors:  O Yamauchi; M Omori; M Ninomiya; M Okuno; H Moriwaki; M Suganuma; H Fujiki; Y Muto
Journal:  Jpn J Cancer Res       Date:  1991-11
  2 in total

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