| Literature DB >> 19701193 |
Tanya Hatzistavrou1, Suzanne J Micallef, Elizabeth S Ng, Jim Vadolas, Edouard G Stanley, Andrew G Elefanty.
Abstract
A human embryonic stem cell (hESC) line that enabled globin-expressing cells to be easily recognized would facilitate optimization of erythroid differentiation in vitro and aid in the identification of hESC-derived erythroid cells in transplanted animals. We describe a genetically modified hESC line, ErythRED, in which expression of RFP, controlled by regulatory sequences from the human beta-globin locus control region, is restricted to maturing erythroid cells.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19701193 DOI: 10.1038/nmeth.1364
Source DB: PubMed Journal: Nat Methods ISSN: 1548-7091 Impact factor: 28.547