Literature DB >> 19699961

Proinflammatory cytokine effects on mesenchymal stem cell therapy for the ischemic heart.

Aaron M Abarbanell1, Arthur C Coffey, John W Fehrenbacher, Daniel J Beckman, Jeremy L Herrmann, Brent Weil, Daniel R Meldrum.   

Abstract

Mesenchymal stem cells (MSCs) hold great promise for improving myocardial recovery after ischemia. The cardiothoracic surgeon is uniquely positioned to be at the forefront of any clinical application of this therapy. As such, a basic understanding of stem cells and the cytokines that affect stem cell function will be an essential component of the surgeon's ever-expanding knowledge base. This review provides: (1) a general overview of stem cells and MSCs in particular, (2) critically analyzes several cytokines known to alter MSC function, and (3) discusses methods to manipulate cytokine-activated MSCs to improve MSC function for potential clinical application.

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Year:  2009        PMID: 19699961     DOI: 10.1016/j.athoracsur.2009.02.093

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  18 in total

1.  Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury.

Authors:  Aaron M Abarbanell; Yue Wang; Jeremy L Herrmann; Brent R Weil; Jeffrey A Poynter; Mariuxi C Manukyan; Daniel R Meldrum
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-02-19       Impact factor: 4.733

2.  Quantitatively analyzing the protective effect of mesenchymal stem cells on cardiomyocytes in single-cell biochips.

Authors:  Zhen Ma; Bruce Z Gao
Journal:  Biotechnol Lett       Date:  2012-03-17       Impact factor: 2.461

3.  Mesenchymal Stem Cells in Cardiology.

Authors:  Ian A White; Cristina Sanina; Wayne Balkan; Joshua M Hare
Journal:  Methods Mol Biol       Date:  2016

Review 4.  Mesenchymal stem cells as a double-edged sword in suppression or progression of solid tumor cells.

Authors:  Fatemeh Norozi; Ahmad Ahmadzadeh; Saeid Shahrabi; Tina Vosoughi; Najmaldin Saki
Journal:  Tumour Biol       Date:  2016-07-20

5.  Human pericytes for ischemic heart repair.

Authors:  Chien-Wen Chen; Masaho Okada; Jonathan D Proto; Xueqin Gao; Naosumi Sekiya; Sarah A Beckman; Mirko Corselli; Mihaela Crisan; Arman Saparov; Kimimasa Tobita; Bruno Péault; Johnny Huard
Journal:  Stem Cells       Date:  2013-02       Impact factor: 6.277

6.  Mesenchymal stem cell-cardiomyocyte interactions under defined contact modes on laser-patterned biochips.

Authors:  Zhen Ma; Huaxiao Yang; Honghai Liu; Meifeng Xu; Raymond B Runyan; Carol A Eisenberg; Roger R Markwald; Thomas K Borg; Bruce Z Gao
Journal:  PLoS One       Date:  2013-02-13       Impact factor: 3.240

7.  Potential role of adult stem cells in obstructive sleep apnea.

Authors:  Isaac Almendros; Alba Carreras; Josep M Montserrat; David Gozal; Daniel Navajas; Ramon Farre
Journal:  Front Neurol       Date:  2012-07-11       Impact factor: 4.003

8.  High targeted migration of human mesenchymal stem cells grown in hypoxia is associated with enhanced activation of RhoA.

Authors:  Grigory Vertelov; Ludmila Kharazi; M G Muralidhar; Givon Sanati; Timothy Tankovich; Alex Kharazi
Journal:  Stem Cell Res Ther       Date:  2013-01-07       Impact factor: 6.832

9.  Exploiting human CD34+ stem cell-conditioned medium for tissue repair.

Authors:  Paul J Mintz; Kai-Wen Huang; Vikash Reebye; Georgios Nteliopoulos; Hong-Shiee Lai; Pal Sætrom; Noriyuki Kasahara; Steen Jensen; Madhava Pai; Myrtle Y A Gordon; Stephen B Marley; Rosemary Behan; Duncan R Spalding; Abdelali Haoudi; Mohamed M Emara; Joanna Nicholls; John J Rossi; Nagy A Habib
Journal:  Mol Ther       Date:  2013-08-28       Impact factor: 11.454

10.  Cardiomyocyte regeneration.

Authors:  Nanako Kawaguchi; Toshio Nakanishi
Journal:  Cells       Date:  2013-01-15       Impact factor: 6.600

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