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Literature DB >> 19699513

A common mechanism in verb and noun naming deficits in Alzheimer's patients.

Amit Almor¹, Justin M Aronoff, Maryellen C MacDonald, Laura M Gonnerman, Daniel Kempler, Houri Hintiryan, Unja L Hayes, Sudha Arunachalam, Elaine S Andersen.

Abstract

We tested the ability of Alzheimer's patients and elderly controls to name living and non-living nouns, and manner and instrument verbs. Patients' error patterns and relative performance with different categories showed evidence of graceful degradation for both nouns and verbs, with particular domain-specific impairments for living nouns and instrument verbs. Our results support feature-based, semantic representations for nouns and verbs and support the role of inter-correlated features in noun impairment, and the role of noun knowledge in instrument verb impairment.

Entities: CellLine Disease Gene Species

Mesh：

Year: 2009 PMID： 19699513 PMCID： PMC2774798 DOI： 10.1016/j.bandl.2009.07.009

Source DB: PubMed Journal: Brain Lang ISSN： 0093-934X Impact factor: 2.381

35 in total

1. Towards a distributed account of conceptual knowledge.

Authors: L K. Tyler; H E. Moss
Journal: Trends Cogn Sci Date: 2001-06-01 Impact factor: 20.229

2. Semantic networks of English.

Authors: G A Miller; C Fellbaum
Journal: Cognition Date: 1991-12

3. An efficient method for estimating semantic similarity based on feature overlap: reliability and validity of semantic feature ratings.

Authors: William S Maki; Marissa Krimsky; Sol Muñoz
Journal: Behav Res Methods Date: 2006-02

A common mechanism in verb and noun naming deficits in Alzheimer's patients.

1. Towards a distributed account of conceptual knowledge.

2. Semantic networks of English.

3. An efficient method for estimating semantic similarity based on feature overlap: reliability and validity of semantic feature ratings.

4. Verb comprehension deficits in probable Alzheimer's disease.

Review 5. Domain-specific knowledge systems in the brain the animate-inanimate distinction.

6. On the nature and scope of featural representations of word meaning.

7. A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity.

8. Is action naming better preserved (than object naming) in Alzheimer's disease and why should we ask?

9. Category-specific semantic deficits in focal and widespread brain damage: a computational account.

10. Charting the progression in semantic dementia: implications for the organisation of semantic memory.

1. Using informative verbal exchanges to promote verb retrieval in nonfluent aphasia.

2. Neural representation of word categories is distinct in the temporal lobe: An activation likelihood analysis.

3. Word retrieval in picture descriptions produced by individuals with Alzheimer's disease.

4. Lexical retrieval in discourse: an early indicator of Alzheimer's dementia.

5. Effects of Noun-Verb Conceptual/ Phonological Relatedness on Verb Production Changes in Broca's Aphasia.

6. Distinct neural mechanisms underlying conceptual knowledge of manner and instrument verbs.

7. A comparison of drill- and communication-based treatment for aphasia.

Review 8. Brain stimulation for combating Alzheimer's disease.

Review 9. Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease (Review).