Literature DB >> 19699259

Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease.

Georges St Laurent1, Mohammad Ali Faghihi, Claes Wahlestedt.   

Abstract

Non-protein-coding RNAs (ncRNAs) play critical roles on many levels of cellular information processing and pervasive expression of ncRNAs in the nervous system could help explain brain complexity. NcRNAs are enriched in the central nervous system and are associated with specific neuroanatomical regions. Additionally, several recent publications have revealed an important role for deregulation of ncRNAs in various human neuropathologies, such as Alzheimer's disease, Parkinson's disease and Fragile X mental retardation. Herein, we summarize reports on functional ncRNA molecules involved in cellular stress response, particularly related to Alzheimer's disease. We conclude that ncRNAs have a prominent role in maintaining precise physiological levels of gene products directly implicated in Alzheimer's disease pathology.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19699259      PMCID： PMC2767472          DOI： 10.1016/j.neulet.2009.08.032

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  76 in total

1.  Antisense transcripts with FANTOM2 clone set and their implications for gene regulation.

Authors:  Hidenori Kiyosawa; Itaru Yamanaka; Naoki Osato; Shinji Kondo; Yoshihide Hayashizaki
Journal:  Genome Res       Date:  2003-06       Impact factor: 9.043

2.  Genome-wide atlas of gene expression in the adult mouse brain.

Authors:  Ed S Lein; Michael J Hawrylycz; Nancy Ao; Mikael Ayres; Amy Bensinger; Amy Bernard; Andrew F Boe; Mark S Boguski; Kevin S Brockway; Emi J Byrnes; Lin Chen; Li Chen; Tsuey-Ming Chen; Mei Chi Chin; Jimmy Chong; Brian E Crook; Aneta Czaplinska; Chinh N Dang; Suvro Datta; Nick R Dee; Aimee L Desaki; Tsega Desta; Ellen Diep; Tim A Dolbeare; Matthew J Donelan; Hong-Wei Dong; Jennifer G Dougherty; Ben J Duncan; Amanda J Ebbert; Gregor Eichele; Lili K Estin; Casey Faber; Benjamin A Facer; Rick Fields; Shanna R Fischer; Tim P Fliss; Cliff Frensley; Sabrina N Gates; Katie J Glattfelder; Kevin R Halverson; Matthew R Hart; John G Hohmann; Maureen P Howell; Darren P Jeung; Rebecca A Johnson; Patrick T Karr; Reena Kawal; Jolene M Kidney; Rachel H Knapik; Chihchau L Kuan; James H Lake; Annabel R Laramee; Kirk D Larsen; Christopher Lau; Tracy A Lemon; Agnes J Liang; Ying Liu; Lon T Luong; Jesse Michaels; Judith J Morgan; Rebecca J Morgan; Marty T Mortrud; Nerick F Mosqueda; Lydia L Ng; Randy Ng; Geralyn J Orta; Caroline C Overly; Tu H Pak; Sheana E Parry; Sayan D Pathak; Owen C Pearson; Ralph B Puchalski; Zackery L Riley; Hannah R Rockett; Stephen A Rowland; Joshua J Royall; Marcos J Ruiz; Nadia R Sarno; Katherine Schaffnit; Nadiya V Shapovalova; Taz Sivisay; Clifford R Slaughterbeck; Simon C Smith; Kimberly A Smith; Bryan I Smith; Andy J Sodt; Nick N Stewart; Kenda-Ruth Stumpf; Susan M Sunkin; Madhavi Sutram; Angelene Tam; Carey D Teemer; Christina Thaller; Carol L Thompson; Lee R Varnam; Axel Visel; Ray M Whitlock; Paul E Wohnoutka; Crissa K Wolkey; Victoria Y Wong; Matthew Wood; Murat B Yaylaoglu; Rob C Young; Brian L Youngstrom; Xu Feng Yuan; Bin Zhang; Theresa A Zwingman; Allan R Jones
Journal:  Nature       Date:  2006-12-06       Impact factor: 49.962

Review 3.  Noncoding RNAs: couplers of analog and digital information in nervous system function?

Authors:  Georges St Laurent; Claes Wahlestedt
Journal:  Trends Neurosci       Date:  2007-11-08       Impact factor: 13.837

4.  Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites.

Authors:  Rickard Sandberg; Joel R Neilson; Arup Sarma; Phillip A Sharp; Christopher B Burge
Journal:  Science       Date:  2008-06-20       Impact factor: 47.728

Review 5.  Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors.

Authors:  Judith Campisi
Journal:  Cell       Date:  2005-02-25       Impact factor: 41.582

6.  MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1.

Authors:  Vincent Boissonneault; Isabelle Plante; Serge Rivest; Patrick Provost
Journal:  J Biol Chem       Date:  2008-11-05       Impact factor: 5.157

Review 7.  Mechanisms of tau-induced neurodegeneration.

Authors:  Khalid Iqbal; Fei Liu; Cheng-Xin Gong; Alejandra Del C Alonso; Inge Grundke-Iqbal
Journal:  Acta Neuropathol       Date:  2009-01-30       Impact factor: 17.088

8.  Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase.

Authors:  Mohammad Ali Faghihi; Farzaneh Modarresi; Ahmad M Khalil; Douglas E Wood; Barbara G Sahagan; Todd E Morgan; Caleb E Finch; Georges St Laurent; Paul J Kenny; Claes Wahlestedt
Journal:  Nat Med       Date:  2008-06-29       Impact factor: 53.440

Review 9.  MicroRNAs (miRNAs) in neurodegenerative diseases.

Authors:  Peter T Nelson; Wang-Xia Wang; Bernard W Rajeev
Journal:  Brain Pathol       Date:  2008-01       Impact factor: 6.508

10.  A mammalian microRNA expression atlas based on small RNA library sequencing.

Authors:  Pablo Landgraf; Mirabela Rusu; Robert Sheridan; Alain Sewer; Nicola Iovino; Alexei Aravin; Sébastien Pfeffer; Amanda Rice; Alice O Kamphorst; Markus Landthaler; Carolina Lin; Nicholas D Socci; Leandro Hermida; Valerio Fulci; Sabina Chiaretti; Robin Foà; Julia Schliwka; Uta Fuchs; Astrid Novosel; Roman-Ulrich Müller; Bernhard Schermer; Ute Bissels; Jason Inman; Quang Phan; Minchen Chien; David B Weir; Ruchi Choksi; Gabriella De Vita; Daniela Frezzetti; Hans-Ingo Trompeter; Veit Hornung; Grace Teng; Gunther Hartmann; Miklos Palkovits; Roberto Di Lauro; Peter Wernet; Giuseppe Macino; Charles E Rogler; James W Nagle; Jingyue Ju; F Nina Papavasiliou; Thomas Benzing; Peter Lichter; Wayne Tam; Michael J Brownstein; Andreas Bosio; Arndt Borkhardt; James J Russo; Chris Sander; Mihaela Zavolan; Thomas Tuschl
Journal:  Cell       Date:  2007-06-29       Impact factor: 41.582
View more
  11 in total

Review 1.  Gene expression in the human brain: the current state of the study of specificity and spatiotemporal dynamics.

Authors:  Oksana Yu Naumova; Maria Lee; Sergei Yu Rychkov; Natalia V Vlasova; Elena L Grigorenko
Journal:  Child Dev       Date:  2012-11-12

Review 2.  Deep sequencing of coding and non-coding RNA in the CNS.

Authors:  Marcel van der Brug; Michael A Nalls; Mark R Cookson
Journal:  Brain Res       Date:  2010-03-20       Impact factor: 3.252

3.  Age-related changes of gene expression in the neocortex: preliminary data on RNA-Seq of the transcriptome in three functionally distinct cortical areas.

Authors:  Oksana Yu Naumova; Dean Palejev; Natalia V Vlasova; Maria Lee; Sergei Yu Rychkov; Olga N Babich; Flora M Vaccarino; Elena L Grigorenko
Journal:  Dev Psychopathol       Date:  2012-11

Review 4.  Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy.

Authors:  Irfan A Qureshi; Mark F Mehler
Journal:  Neurotherapeutics       Date:  2013-10       Impact factor: 7.620

5.  Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy.

Authors:  Suzanne G Rzuczek; Mark R Southern; Matthew D Disney
Journal:  ACS Chem Biol       Date:  2015-09-28       Impact factor: 5.100

6.  Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.

Authors:  Jessica L Childs-Disney; Jason Hoskins; Suzanne G Rzuczek; Charles A Thornton; Matthew D Disney
Journal:  ACS Chem Biol       Date:  2012-03-05       Impact factor: 5.100

7.  Experimental RNomics and genomic comparative analysis reveal a large group of species-specific small non-message RNAs in the silkworm Bombyx mori.

Authors:  Dandan Li; Yanhong Wang; Kun Zhang; Zhujin Jiao; Xiaopeng Zhu; Geir Skogerboe; Xiangqian Guo; Viswanathan Chinnusamy; Lijun Bi; Yongping Huang; Shuanglin Dong; Runsheng Chen; Yunchao Kan
Journal:  Nucleic Acids Res       Date:  2011-01-11       Impact factor: 16.971

8.  The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA.

Authors:  Philipp Kapranov; Georges St Laurent; Tal Raz; Fatih Ozsolak; C Patrick Reynolds; Poul H B Sorensen; Gregory Reaman; Patrice Milos; Robert J Arceci; John F Thompson; Timothy J Triche
Journal:  BMC Biol       Date:  2010-12-21       Impact factor: 7.431

9.  A novel collection of snRNA-like promoters with tissue-specific transcription properties.

Authors:  Sonia Garritano; Arianna Gigoni; Delfina Costa; Paolo Malatesta; Tullio Florio; Ranieri Cancedda; Aldo Pagano
Journal:  Int J Mol Sci       Date:  2012-09-11       Impact factor: 6.208

10.  Bioregulatory systems medicine: an innovative approach to integrating the science of molecular networks, inflammation, and systems biology with the patient's autoregulatory capacity?

Authors:  Alyssa W Goldman; Yvonne Burmeister; Konstantin Cesnulevicius; Martha Herbert; Mary Kane; David Lescheid; Timothy McCaffrey; Myron Schultz; Bernd Seilheimer; Alta Smit; Georges St Laurent; Brian Berman
Journal:  Front Physiol       Date:  2015-08-19       Impact factor: 4.566
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.