Literature DB >> 19699233

Viral vector approaches to modify gene expression in the brain.

Alessandro Papale1, Milica Cerovic, Riccardo Brambilla.   

Abstract

The use of viral vectors as gene transfer tools for the central nervous system has seen a significant growth in the last decade. Improvements in the safety, efficiency and specificity of vectors for clinical applications have proven to be beneficial also for basic neuroscience research. This review will discuss the viral systems currently available to neuroscientists and some of the recent achievements in the study of synaptic function, memory and drug addiction.

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Year:  2009        PMID: 19699233     DOI: 10.1016/j.jneumeth.2009.08.013

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  16 in total

1.  5-HT1B autoreceptors differentially modulate the expression of conditioned fear in a circuit-specific manner.

Authors:  Y Liu; M A Kelly; T J Sexton; J F Neumaier
Journal:  Neuroscience       Date:  2015-04-20       Impact factor: 3.590

2.  Cell-type specific oxytocin gene expression from AAV delivered promoter deletion constructs into the rat supraoptic nucleus in vivo.

Authors:  Raymond L Fields; Todd A Ponzio; Makoto Kawasaki; Harold Gainer
Journal:  PLoS One       Date:  2012-02-21       Impact factor: 3.240

Review 3.  Genetic approaches to investigate the role of CREB in neuronal plasticity and memory.

Authors:  Angel Barco; Hélène Marie
Journal:  Mol Neurobiol       Date:  2011-09-23       Impact factor: 5.590

Review 4.  Cell-type specific expression of oxytocin and vasopressin genes: an experimental odyssey.

Authors:  H Gainer
Journal:  J Neuroendocrinol       Date:  2012-04       Impact factor: 3.627

5.  In vivo rapid gene delivery into postmitotic neocortical neurons using iontoporation.

Authors:  Andres De la Rossa; Denis Jabaudon
Journal:  Nat Protoc       Date:  2014-12-04       Impact factor: 13.491

6.  Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones.

Authors:  Thomas H Hutson; Edmund Foster; John M Dawes; Robert Hindges; Rafael J Yáñez-Muñoz; Lawrence D F Moon
Journal:  J Gene Med       Date:  2012-05       Impact factor: 4.565

Review 7.  Novel approaches for the delivery of therapeutics in ischemic stroke.

Authors:  Saeideh Nozohouri; Ali Ehsan Sifat; Bhuvaneshwar Vaidya; Thomas J Abbruscato
Journal:  Drug Discov Today       Date:  2020-01-21       Impact factor: 7.851

Review 8.  Drug delivery systems for the treatment of ischemic stroke.

Authors:  Taiyoun Rhim; Dong Yun Lee; Minhyung Lee
Journal:  Pharm Res       Date:  2013-01-10       Impact factor: 4.200

9.  The use of an adeno-associated viral vector for efficient bicistronic expression of two genes in the central nervous system.

Authors:  Thomas Haynes Hutson; Claudia Kathe; Sean Christopher Menezes; Marie-Claire Rooney; Hansruedi Bueler; Lawrence David Falcon Moon
Journal:  Methods Mol Biol       Date:  2014

10.  Cell-type specific expression of the vasopressin gene analyzed by AAV mediated gene delivery of promoter deletion constructs into the rat SON in vivo.

Authors:  Todd A Ponzio; Raymond L Fields; Omar M Rashid; Yasmmyn D Salinas; Daniel Lubelski; Harold Gainer
Journal:  PLoS One       Date:  2012-11-14       Impact factor: 3.240

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