Literature DB >> 19699166

LAT polices T cell activation.

Rebecca Brownlie1, Rose Zamoyska.   

Abstract

Mutations in the adaptor molecule LAT can lead to autoimmunity. In this issue of Immunity, Mingueneau et al. (2009) describe how this may not be a failure of central tolerance.

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Year:  2009        PMID: 19699166     DOI: 10.1016/j.immuni.2009.08.002

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  6 in total

1.  Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells.

Authors:  Darienne R Myers; Tannia Lau; Evan Markegard; Hyung W Lim; Herbert Kasler; Minghua Zhu; Andrea Barczak; John P Huizar; Julie Zikherman; David J Erle; Weiguo Zhang; Eric Verdin; Jeroen P Roose
Journal:  Cell Rep       Date:  2017-05-23       Impact factor: 9.423

2.  GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells.

Authors:  Mahmood Y Bilal; Elizabeth Y Zhang; Brittney Dinkel; Daimon Hardy; Thomas M Yankee; Jon C D Houtman
Journal:  Cell Signal       Date:  2015-01-28       Impact factor: 4.315

3.  Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses.

Authors:  Matthew J Billard; Amanda L Gruver; Gregory D Sempowski
Journal:  PLoS One       Date:  2011-03-18       Impact factor: 3.240

4.  TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapter.

Authors:  Ji-Ji Xie; Jia-Qi Liang; Liang-Hui Diao; Amnon Altman; Yingqiu Li
Journal:  J Immunol       Date:  2013-03-20       Impact factor: 5.422

5.  Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression.

Authors:  Evan Markegard; Evan Trager; Chih-wen Ou Yang; Weiguo Zhang; Arthur Weiss; Jeroen P Roose
Journal:  PLoS One       Date:  2011-09-26       Impact factor: 3.240

6.  GRB2 Nucleates T Cell Receptor-Mediated LAT Clusters That Control PLC-γ1 Activation and Cytokine Production.

Authors:  Mahmood Yousif Bilal; Jon C D Houtman
Journal:  Front Immunol       Date:  2015-03-30       Impact factor: 7.561

  6 in total

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