Literature DB >> 19698768

Promising candidates in clinical trials against multidrug-resistant tuberculosis (MDR-TB) based on natural products.

Marcus Vinícius Nora de Souza1.   

Abstract

In the twenty first century the interest in new anti-tuberculosis drugs based on natural products, specially against MDR (multidrug-resistant) and XDR (extensively drug resistant) tuberculosis (TB) is growing, as indicated by the increasing number of publications in this field. Some natural products, semisynthetic or synthetic compounds based on nature are in clinical studies and are the subject of this article.

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Year:  2009        PMID: 19698768     DOI: 10.1016/j.fitote.2009.07.010

Source DB:  PubMed          Journal:  Fitoterapia        ISSN: 0367-326X            Impact factor:   2.882


  4 in total

1.  Stereochemical analysis of leubethanol, an anti-TB-active serrulatane, from Leucophyllum frutescens.

Authors:  Gloria M Molina-Salinas; Verónica M Rivas-Galindo; Salvador Said-Fernández; David C Lankin; Marcelo A Muñoz; Pedro Joseph-Nathan; Guido F Pauli; Noemí Waksman
Journal:  J Nat Prod       Date:  2011-08-22       Impact factor: 4.050

Review 2.  Pharmaceutical aerosols for the treatment and prevention of tuberculosis.

Authors:  Shumaila N M Hanif; Lucila Garcia-Contreras
Journal:  Front Cell Infect Microbiol       Date:  2012-09-07       Impact factor: 5.293

3.  In vitro antimicrobial activity of extracts from plants used traditionally in South Africa to treat tuberculosis and related symptoms.

Authors:  Balungile Madikizela; Ashwell Rungano Ndhlala; Jeffrey Franklin Finnie; Johannes Van Staden
Journal:  Evid Based Complement Alternat Med       Date:  2013-03-05       Impact factor: 2.629

4.  Aqueous Molecular Dynamics Simulations of the M. tuberculosis Enoyl-ACP Reductase-NADH System and Its Complex with a Substrate Mimic or Diphenyl Ethers Inhibitors.

Authors:  Camilo Henrique da Silva Lima; Ricardo Bicca de Alencastro; Carlos Roland Kaiser; Marcus Vinícius Nora de Souza; Carlos Rangel Rodrigues; Magaly Girão Albuquerque
Journal:  Int J Mol Sci       Date:  2015-10-07       Impact factor: 5.923

  4 in total

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