OBJECTIVE: Differentiating neoplastic from nonneoplastic bone marrow changes on imaging can be challenging. MRI provides the most helpful information when using T1-weighted and opposed-phase (chemical shift) sequences. We discuss the MRI assessment of bone marrow in the context of a complex clinical case. CONCLUSION: The case shows a false-positive result of opposed-phase imaging of bone marrow, which was a postinflammatory cause resulting in marrow fibrosis that mimicked neoplastic marrow infiltration and necessitated biopsy for definitive diagnosis.
OBJECTIVE: Differentiating neoplastic from nonneoplastic bone marrow changes on imaging can be challenging. MRI provides the most helpful information when using T1-weighted and opposed-phase (chemical shift) sequences. We discuss the MRI assessment of bone marrow in the context of a complex clinical case. CONCLUSION: The case shows a false-positive result of opposed-phase imaging of bone marrow, which was a postinflammatory cause resulting in marrow fibrosis that mimicked neoplastic marrow infiltration and necessitated biopsy for definitive diagnosis.
Authors: Chad A Kohl; F Spencer Chivers; Roxanne Lorans; Catherine C Roberts; Mark J Kransdorf Journal: Skeletal Radiol Date: 2014-04-30 Impact factor: 2.199
Authors: Christina S Gee; Jennifer T K Nguyen; Candice J Marquez; Julia Heunis; Andrew Lai; Cory Wyatt; Misung Han; Galateia Kazakia; Andrew J Burghardt; Dimitrios C Karampinos; Julio Carballido-Gamio; Roland Krug Journal: J Magn Reson Imaging Date: 2014-11-25 Impact factor: 4.813
Authors: Chandani Thorning; Wladyslaw M W Gedroyc; Philippa A Tyler; Elizabeth A Dick; Elaine Hui; Jonathan Valabhji Journal: Diabetes Care Date: 2010-04-22 Impact factor: 17.152